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Why Are The Insides Of My Legs Still Extremely Painful Even After Treating Pedal Edema With Amlodipine?

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Posted on Thu, 4 Apr 2024
Question: I took amlopidine for about a month, despite the swelling in ankles. It has been over a month now, and even with most swelling now gone, the insides of my lower legs are extremely painful, with stabbing pain, and constant pain of varying degrees. I have tried the obvious; compression stockings, putting them up as much as possible, pain meds, and so on. Will it ever get better? How long should I expect? My lifestyle has been changed, let alone the awful pain. Nobody seems to give me a good answer. I am 73 years old and otherwise in reasonably good health. I don't know what to do and this is torture.
doctor
Answered by Dr. Noble Zachariah (1 hour later)
Brief Answer:
Better to use another blood pressure medication without this side effect.

Detailed Answer:
Hello,

Welcome and thanks for your query.
The swelling of legs, when it occurs, is an uncomfortable side effect. It is due to the dilatation of the small blood vessel and the exodus of the fluid into the surrounding tissues.
Since there are other effective blood pressure medication without this side effect, it would be better for you to request your doctor to change to one of those than suffer the torturing side effect.
Do get back to me with your input.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Noble Zachariah (1 hour later)
This isn't a question about blood pressure meds. I was later told by more of a specialist that I never needed to take any of them. Of course I stopped the amlopidine; just wish I had never taken it. I need to know how to make the pain in my inner legs go away. I took the last of that dreadful drug on April 27, and still have terrible leg pain. I have taken lasix, but legs are not really swollen now. Am I making it worse when I put on support stockings and make myself walk most of the day? How long will it take for the nerves to heal? I had veins checked and it is not the problem. I am healthy except for this leg issue. My blood pressure, by the way, has returned to the normal readings that I had for the last decade, without any of the awful meds. I just want to get rid of leg pain. Only on insides of legs. I live on Tylenol. Will it eventually get better? How long would I expect for that to happen? My life is interrupted and the pain is terrible.
doctor
Answered by Dr. Noble Zachariah (9 hours later)
Brief Answer:
Discussion continued

Detailed Answer:
Welcome back.
Sorry for the delay in replying as I live in a different time zone.
The effect of amlodipine doesn't last this long. It is likely to be a painful neuropathy. You need to take vitamin B1 and B12 which are present in Neurobion and available OTC. You also need to take a medicine which decreases the pain due to a neuropathy. It is Gabapentin ( Neurontin ). This is a prescription medicine. Take 300 mg at bed time. It is safe and has hardly any side effect except producing sleep at that dose. You can take panadol for pain if necessary but avoid opiates.

Do get back to me if you have further questions.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Noble Zachariah

Internal Medicine Specialist

Practicing since :1974

Answered : 2319 Questions

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Why Are The Insides Of My Legs Still Extremely Painful Even After Treating Pedal Edema With Amlodipine?

Brief Answer: Better to use another blood pressure medication without this side effect. Detailed Answer: Hello, Welcome and thanks for your query. The swelling of legs, when it occurs, is an uncomfortable side effect. It is due to the dilatation of the small blood vessel and the exodus of the fluid into the surrounding tissues. Since there are other effective blood pressure medication without this side effect, it would be better for you to request your doctor to change to one of those than suffer the torturing side effect. Do get back to me with your input.