
I have been on Tamoxifen for 4 years. I wish

A brief stop of Tamoxifen is is not a problem.
Detailed Answer:
Hello dear and welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.
I understand your concern.
One week is a very short period.
Even if you stop taking Tamoxifen for a week nothing happens and you will not have cold turkey symptoms.
Clarithromicin and Tamoxifen influence in the metabolism of each other.
If you reduce the dose, the risk of the side effects is still possible.
So, I would recommend to stop Tamoxifen for a week and resume with your regular dosing after the trip.
I also recommend to tell your doctor when you will have your periodic visit.
Hope I have answered your query. Let me know if I can assist you further.

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