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I Analyzed My Past Autoimmune Tests And Found That They
Question: I analyzed my past autoimmune tests and found that they fluctuated. Can you tell me if this is significant? For instance, my ANA was negative, 1:40, 1:80, negative and 1:80. My dsDNA was positive then negative in the same month. Please see below:
2015/08/27 Negative ANA
2015/11/06 Positive 1:40 ANA SPECKLED PATTERN
2015/11/06 Negative <10 TITER dsDNA Antibody, IFA
2015/11/06 Negative SJOGREN'S ANTIBODIES
2015/11/06 Negative SM & RNP ANTIBODIES
2015/11/06 Negative IMMUNOGLOBULINS IGG IGA IGM
2015/11/06 Negative 14 MM/HR Sedimentation Rate (ESR)
2015/11/06 Negative 0.21 MG/DL C-Reactive Protein
2015/11/06 Negative Anticardiolipin IgG IgA IgM
2015/11/20 Negative 0 copies/PCR EPSTEIN-BARR VIRUS, DNA QUANT
2015/11/20 Positive 48 MG/DL Protein, CSF
2015/11/20 Positive 36.6 MG/DL Albumin, CSF
2016/09/20 Positive 1:80 ANA DIFFUSE HOMOGENEOUS PATTERN
2017/11/08 Positive 1:80 ANA HOMOGENEOUS
2018/07/09 Positive 1:40 ANA HOMOGENEOUS AND NUCLEOLAR
2018/10/06 Negative ANA
2018/10/08 Positive 305 dsDNA AB EIA
2018/10/23 Positive 1:80 ANA HOMOGENEOUS
2018/10/23 Positive 3.1 SJOGREN'S ANTIBODY (SS-A)
2018/10/23 Negative 2 DNA (DS) ANTIBODY
2015/08/27 Negative ANA
2015/11/06 Positive 1:40 ANA SPECKLED PATTERN
2015/11/06 Negative <10 TITER dsDNA Antibody, IFA
2015/11/06 Negative SJOGREN'S ANTIBODIES
2015/11/06 Negative SM & RNP ANTIBODIES
2015/11/06 Negative IMMUNOGLOBULINS IGG IGA IGM
2015/11/06 Negative 14 MM/HR Sedimentation Rate (ESR)
2015/11/06 Negative 0.21 MG/DL C-Reactive Protein
2015/11/06 Negative Anticardiolipin IgG IgA IgM
2015/11/20 Negative 0 copies/PCR EPSTEIN-BARR VIRUS, DNA QUANT
2015/11/20 Positive 48 MG/DL Protein, CSF
2015/11/20 Positive 36.6 MG/DL Albumin, CSF
2016/09/20 Positive 1:80 ANA DIFFUSE HOMOGENEOUS PATTERN
2017/11/08 Positive 1:80 ANA HOMOGENEOUS
2018/07/09 Positive 1:40 ANA HOMOGENEOUS AND NUCLEOLAR
2018/10/06 Negative ANA
2018/10/08 Positive 305 dsDNA AB EIA
2018/10/23 Positive 1:80 ANA HOMOGENEOUS
2018/10/23 Positive 3.1 SJOGREN'S ANTIBODY (SS-A)
2018/10/23 Negative 2 DNA (DS) ANTIBODY
Brief Answer:
hi, following these don't have much significance
Detailed Answer:
hi,
yes, I agree that your immunological tests have been fluctuating.
however, as you might have observed the test for ANA has more or less been in the same range of negative to 40 to 80.
these are considered to be low titers,
I would like to let you know that we generally don't repeat these tests as they may vary during the course of illness, however don't hold much significance as we don't follow this for treatment, fluctuations can happen, but generally the titers are there in the same range like mild, moderate or severe,
titers of ds DNA are sometimes followed in diseases like lupus nephritis, and were thought to correlate with disease activity. but this is controversial.
so I suggest that there is no need to follow these, our main aim is to follow the disease symptoms associated with your autoimmune disease.
regards
hi, following these don't have much significance
Detailed Answer:
hi,
yes, I agree that your immunological tests have been fluctuating.
however, as you might have observed the test for ANA has more or less been in the same range of negative to 40 to 80.
these are considered to be low titers,
I would like to let you know that we generally don't repeat these tests as they may vary during the course of illness, however don't hold much significance as we don't follow this for treatment, fluctuations can happen, but generally the titers are there in the same range like mild, moderate or severe,
titers of ds DNA are sometimes followed in diseases like lupus nephritis, and were thought to correlate with disease activity. but this is controversial.
so I suggest that there is no need to follow these, our main aim is to follow the disease symptoms associated with your autoimmune disease.
regards
Above answer was peer-reviewed by :
Dr. Kampana
Thanks. Would the levels that I have warrant treatment with Cytoxin 20 mg once a month for six months? Or is it too mild to need such treatment?
Brief Answer:
It was fine
Detailed Answer:
no, as I mentioned earlier I think the values are fine and not significant enough to warrant treatment.
It was fine
Detailed Answer:
no, as I mentioned earlier I think the values are fine and not significant enough to warrant treatment.
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Above answer was peer-reviewed by :
Dr. Prasad
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