Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

155 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Having dry cough and runny nose. Not cured by prescribed medicine. Is it safe to take Piriton Cs?

Answered by
Dr. Sujoy Khan

Allergist and Immunologist

Practicing since :1999

Answered : 584 Questions

Posted on Tue, 5 Feb 2013 in Asthma and Allergy
Question: I am 28 and on three anti seizure medicines, viz Carbamazepine 200 mg 2-0-2, Levetiracetam 500 mg 2-0-2 and Lamotrigine 100 mg 2-0-2. For the past two weeks I am having cough, mostly dry
irritating one and running nose. I took as per prescription of a doctor Cefixime, Bromhexine, etc. but to no relief. Doing gorgling with hot water, steam inhalation, etc. Is is safe to now try Piriton Cs which contains Chlorpheniramine maleate 4 mg and Dextromethorphan 10 mg per 5 ml. The dosage is 5ml every 4 hours. Thanks. XXXXXXX ( email YYYY@YYYY )
Answered by Dr. Sujoy Khan 1 hour later
Welcome to Healthcare Magic and thank you for writing to us.

It is possible that you have dust allergy and allergy testing with either skin prick tests or blood test (specific IgE) against all aero-allergens may reveal the cause. However, non-allergic rhinitis is also a possibility when all tests (including total IgE is low) are negative.

The treatment is antihistamines such as cetirizine 10mg twice daily and flixonase nasal spray 2 sprays per nostril twice daily.
Cough syrups are not helpful for rhinitis related cough.
Also if you have acid reflux, you can have a cough for which either esomeprazole or rabeprazole once daily will be helpful.

Best Wishes.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Follow up: Dr. Sujoy Khan 1 hour later
Since I am on anti seizure medication, my neurologist had advised about avoiding
Cetrizine 10mg, CPM 8 mg and Ciprofloxacin among many drugs. Have you taken this into account? Even Azithromycin and Cefixime are to be avoided. As such
Piriton CS can be tried as in the past some relief was felt in cases of dry cough. Immediately it is not possible to get the tests done. Till then I have to take something to get some relief. I hope I have made my point clear. Thanks.
Answered by Dr. Sujoy Khan 9 hours later
You will need to get in touch with your neurologist to find out the reason for avoiding the mentioned drugs.
Some neurological conditions such as myasthenia gravis you need to avoid antibiotics and anticholinergic drugs, but I am not sure then what your exact neuological diagnosis is.
If cetirizine was specifically asked to be avoided, you can ask him about fexofenadine 120 or 180mg OR loratidine 10mg.
At the same tome, enquire about use of steroid nasal sprays, whether it is contraindicated or not.
Try and sparingly use the cough suppressant.

Best Wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Follow up: Dr. Sujoy Khan 4 hours later

The simple question that comes to mind is whether if there are any drugs, including the ones that you have mentioned, which
Can trigger seizure in a patient who is under anit-seizure medication. Thank you for your attention. Please give final
Clarification and close the case.
Answered by Dr. Sujoy Khan 4 hours later

I agree with you entirely that the question is simple enough - do antihistamines trigger seizure episodes? However, the answer is just not straight forward given the complexity of epileptiform disorders, hence my suggestion to discuss with your neurologist.

As far as evidence goes, a rare adverse effect of cetirizine happens to be convulsions (see link: underdesirable effects - WWW.WWWW.WW uk/emc/medicine/0000/spc#UNDESIRABLE_EFFECTS).
However, I have never seen a patient who was affected by this side effect.

With fexofenadine: there is none such reported
WWW.WWWW.WW uk/EMC/medicine/6659/SPC/Telfast+120mg+film-coated+tablets/#UNDESIRABLE_EFFECTS

With Loratadine: no such side effect has been reported
link: WWW.WWWW.WW uk/EMC/medicine/0000/SPC/Clarityn+Allergy+10mg+Tablets/#UNDESIRABLE_EFFECTS

I hope that answers your question.
Best Wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,   ,   ,  
Drug/Medication ,   ,   ,   ,   ,   ,  

Recent questions on  Seizure

doctor1 MD

Dear Sir/ Madam, My name is Sonia, I suffer from mild epilepsy. I haven t had a seizure for 1yr and 2 months. Without sounding strange I tend to hear at times a screeching sound like when you scratch a balloon. Does this mean anything? Is it linked to my epilepsy? I take Carbamazephine 500mg in the morning, 100mg in the afternoon and 500mg in the evening. I can see the side effects it has on me although I am glad its stopping me from having physical fits. Side effects include gaining weight, my intellect has become slower and I find it hard to grasp certain info. I feel depressed at times and now this screeching noise is odd. What can be the cause of this? I use to have a very slight stamner when I was younger but kind of grew out of it when I was younger. You couldn t tell I have one but occasionally it comes out. Just recently its bugging me, probably because I am stressed. Could you give me any advice?

doctor1 MD

Hello. I am in my early fifties, and have always had issues with constipation. I eat a very well balanced diet, full of green vegetables, lean protein choices, and copious water. I don t drink alcohol, though I am on an anti convulsant since having had one seizure twenty years ago. I am active, strong, and fit. I ve had recently tried magnesium citrate, and have finally found some reliable relief. I ve heard so many conflicting opinions on the goodness of magnesium to its condemnation as a chronic addition to my evening routine. Is there a definitive answer? I will be asking my doctor , as I ve neglected to address this issue with her before. May I get yet one more opinion? Thanking you I advance, Cathy

doctor1 MD

my wife had a recent seizure, is on seizure meds, and is having withdrawal symptoms withdrawing from tramadol. she has not slept in 4 days. She took ambien for two days and still is not sleepiing. i am waiting for her dr to call me back, but should i take her to the ER

doctor1 MD

I am trying to find a pain management doctor for my daughter. The standard procedure in this area seems to be" 1. Give the patient enough pain medication to treat the pain. 2. Cut the pain medication in half My daughter has fibromyalgia ,...

doctor1 MD

pristiq desvenlafaxine 100 mg and sandomigran 500 mcg what side effects can there be

doctor1 MD

Hello Doctor, I don't feel good. Feel a little bit dizzy, What's wrong with me? What can I do? XXXX