Have moderate pulmonary hypertension and microvascular angina. Could this be related to FSGS stage 3?
Also, I have a positive XXXXXXX nucleolar pattern @ 1:40, Abnormal protein bands 1&2 in my serum and urine (H) negative immunofixation serum and urine for M protein and Beta globulin and gamma globulin peaks... SPEP is normal, dsANA is negative... Could I have a form of Myeloma or Amyloidosis??
It is a possibility that you may have myeloma. You actually need further investigation in the form of a bone marrow exam to rule out malignant cellls. Special stains for amyloid also will have to be done.
The pulmonary Hypertension could be related to a hypercoagulable state.
Amyloid state can be diagnosed by a XXXXXXX scan (scintigraphic imaging ). Rest of your symptoms can be explained by this.
You need to be under a multi-disciplinary team to work out the treatment plan.
Hope I have answered your query. Let me know if I can assist you further.
Wish you good health.
Thanks again for writing back.
An autoimmune disease can cause generalised increase in globulin levels; but as you have a spike that is less likely. Moreover C3 and C4 levels would be generally low in autoimmune disease and not high because of consumption in immune complexes.
Besides those, the antinuclear antibody (ANA) titer is not very high to suggest an autoimmune disease.
Hope I have clarified all your doubts. Should you have any other doubts/concerns; I will be available to clarify.
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