Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
152 Doctors are Online

HDL cholesterol is elevated. Taking Lovastatin. Suggest?

User rating for this question
Very Good
Answered by

Practicing since : 1998
Answered : 1306 Questions
My bad HDL cholesterol has risen from 115 to 150 over the past year even though I am eating better.
I am taking 20mg. of Lovastatin and have done so for the past decade. Would a change of drugs be advisable?
Posted Sun, 22 Sep 2013 in Hypertension and Heart Disease
Answered by Dr. Sukhvinder Singh 1 hour later
Brief Answer:
please provide details.

Detailed Answer:
Respected Sir/ Madam,
1. Bad cholesterol is LDL and not HDL. I would request you to post your complete lipid profile so that I can tell you in detail about this.
2. Please also tell the following things so that exact interpretation can be done:-
a. Your age and gender.
b. If you have diabetes/ stroke/ anginal heart disease/ kidney disease/ carotid artery stenosis/ peripheral arterial disease?
c. Do you smoke?
d. Do you have high blood pressure.
e. Do you have history of heart attack/ angina in blood related family member? If yes , at what age it started?
f. Please also share any other medical illness and all your current medicines.
Waiting for your mail.
Sukhvinder Singh
Above answer was peer-reviewed by
Follow-up: HDL cholesterol is elevated. Taking Lovastatin. Suggest? 13 hours later
The Lipid Panel is as follows:
Cholesterol 188
Triglycerides 90
HDL 43
LDL C 150
I am a 68 year old male
No diabetes/stroke/anginal heart disease/kidney disease/carotid artery stenosis/peripheral arterial disease
Never smoked
BP is under control with Lisinopril and Norvasc at about 125/70
Mother had heart surgury at about 72, but father died at 95
No other medical problems. In fact, I am quite healthy other than the high blood pressure. I am very active and work 12 hour days, play tennis, walk, etc.
The other current medications inclue 150mg. of Wellbutrin which I only started taking about two months ago and I also take 2.5mg. of Cialis for BHP.
Answered by Dr. Sukhvinder Singh 1 hour later
Brief Answer:
You have more than one option.

Detailed Answer:
Respected Sir
1. The target LDL cholesterol level in your case is 130 mg%. Since you have levels 20mg% more than desired levels, it needs intervention. First intervention is life style modification. This includes Maintaining optimal weight (BMI~23), diet XXXXXXX in vegetables/ fruits/ cereals/ legumes/ nuts and low in saturated fats/ sweets/ processed foods & to do daily supervised exercise. This trial should go on for 6 weeks and levels reassessed. If they start improving wait for another 6 weeks and recheck. If the level is below 130 mg% continue same.
2. If you are already following life style modifications or your levels do not come to less than 130mg% after 12 weeks of life style changes, then you need to either change your drug or increase the dose of drug after obtaining a prescription from your local doctor.
Hope this clarifies the issue.
Feel free to discuss further if there is anything.
Sukhvinder Singh
Above answer was peer-reviewed by
Follow-up: HDL cholesterol is elevated. Taking Lovastatin. Suggest? 1 hour later
Thank you for informing me of the target LDL level. I had not been informed of that before. I know about diet and actually do XXXXXXX all of the suggestions that you made. I also exercise regularly. My BMI is at 26, so I am a bit heavy.
2. I have suggested changing the drug as I believe that in some cases, this is a way to lesson the problem. I have increased the intake of Lovastatin from 20mg. to 40mg., in the past, but became victim of muscle cramping and discomfort which disappeared when I reduced the dose to 20mg.
Do you believe that there is a statin that I might consider?
Answered by Dr. Sukhvinder Singh 5 hours later
Brief Answer:
Yes there are other options.

Detailed Answer:
Respected Sir
1. You definitely need to work on your weight. You are right; muscle weakness/ cramps/ fatiguability are well known side effects of statins.
2. There are more statin drugs and to some extent better than lovastatin available in the market. I prefer using Atorvastatin or Rosuvastatin in my patients. Atorvastatin has robust data in its favor and Rosuvastatin was marginally better whenever compared to Atorvastatin. You can get a prescription of one of these two after discussing with your local physician.
Hope this helps.
Sukhvinder Singh
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Medical Topics

The user accepted the expert's answer

Ask a Cardiologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor