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Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Good morning (my time): I came across a product that

Answered by
Dr.
Dr. Bhanu Partap

Cardiologist

Practicing since :2010

Answered : 2154 Questions

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Posted on Thu, 31 Jan 2019 in Hypertension and Heart Disease
Question: Good morning (my time):
I came across a product that is said to slow atherosclerosis progression as written up in the Lancet Magazine. It is called Pycnogenol. A human controlled trial showed that this substance was able to improve endothelial function in patients with CAD, an effect that helps limit the progression of atherosclerosis. Have you heard of it please?
doctor
Answered by Dr. Bhanu Partap 1 hour later
Brief Answer:
Please refer to the detailed answer below

Detailed Answer:
Hello

It’s basically a herbal extract from pine which has come clinical studies or trials been conducted for ADHD attention deficit hyperactivity disorder.

For CAD there has not been any conclusive studies or data being published. Neither have we ever used nor much heard about it being practiced in cardiology.

It’s advisable not to use any such product without medical advice or supervision.

I hope this information will guide you properly.

Kind Regards
Dr Bhanu Partap
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Bhanu Partap 2 hours later
Disagree...I sent you the link which has the medical studies....
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Follow up: Dr. Bhanu Partap 1 hour later
Hi Dr. Bartap ~ below is the link with the studies I discussed. Please take the time to check this out, and get back to me.
https://www.lifeextension.com/magazine/2016/2/slow-the-progression-of-atherosclerotic-plaque/page-01?p=1

I do not have CAD ...I have PAD and NIC...
THank you,
m. reilley, MA, tEFL
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Follow up: Dr. Bhanu Partap 21 minutes later
Here are some good references based on medical studies:

https://journals.lww.com/cardiovascularpharm/Fulltext/1998/10000/Endothelium_Dependent_Vascular_Effects_of.1.aspx
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Follow up: Dr. Bhanu Partap 3 minutes later
And some more =

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/

Cheers!
doctor
Answered by Dr. Bhanu Partap 11 hours later
Brief Answer:
Hello again

Detailed Answer:
Thanks for the reference, appreciate that.

These studies which you are giving references of are of animal models (rats).

As I said earlier I have not come across any conclusive evidence based results for humans.

With Regards
Dr Bhanu Partap

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Bhanu Partap 8 hours later
Here you go Sir...
https://bmcclinpharma.biomedcentral.com/articles/10.1186/1472-6904-6-4

https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-11-11

https://www.sciencedirect.com/science/article/pii/S0000

https://genesandnutrition.biomedcentral.com/articles/10.1007/s12263-009-0135-4

Cheers!


doctor
Answered by Dr. Bhanu Partap 55 minutes later
Brief Answer:
Hello again

Detailed Answer:
Looks like you have done some extensive research on this.

Thanks for updating me on this. As you have asked me that Have I heard of it.

But we are not using this as of now.

If you are not be satisfied with the answer, so with all due respect sir you can go for your refund.

With Regards
Dr Bhanu Partap

CHEERS !!!
Above answer was peer-reviewed by : Dr. Prasad
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