Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
182 Doctors are Online

Fear of syphilis. Tested RPR positive during pregnancy. Have high vitamin D1 level. Related to Lyme disease?

User rating for this question
Very Good
Answered by

Internal Medicine Specialist
Practicing since : 2001
Answered : 2272 Questions
I have always been concerned about STDs. Every once in a while my concern comes back even though I have been married and in a monogamous relationship for many years. I have a fear of syphillis. I have never had symptoms but I am worried about it from many years ago in high school, about 18 years now. I was tested with the RPR in my first pregnancy and that was 9 years ago and then 2 years ago with my second pregnancy and both were nonreactive. Could I still have this? I am obsessing that I will get nuerosyphillis. i am worried about accuracy or would that have been picked up in one of those tests? Do you know the accuracy percentages?
I've just recently had a vitamin d 1, 25 hydroxy test come up high, so I'm panicking about that. It was at 99. I read it could be related to autoimmune processes, including Lyme disease and lymphoma. I'm assuming that since Lyme and syphills are similar that that would be the same case??
Posted Sun, 7 Apr 2013 in Medicines and Side Effects
Answered by Dr. Ram Choudhary 7 hours later
Hi,You seem to be undue anxiously about syphilis, while you have practically rule out the possibility of syphilis in your case.In suspected syphilis, first perform nontreponemal serology screening using the Venereal Disease Research Laboratory(VDRL), rapid plasma reagin (RPR) tests. These tests have good sensitivity and specificity.Sensitivity of the VDRL and RPR tests areestimated to be 78-86% for detecting primary syphilis, 100% for detecting secondary syphilis, and 95-98% for detecting tertiary syphilis. Specificity ranges from 85-99% and may be reduced in individuals who have coexisting conditions (ie, collagenvascular disease, pregnancy, intravenousdrug use, advanced malignancy, tuberculosis,malaria, viral and rickettsial diseases).VDRL test results turn positive 1-2 weeksafter chancre formation. Nontreponemal tests usually become nonreactive with time after treatment.You should not be worried any more regarding syphilis.I wish you a great health.
Above answer was peer-reviewed by
Follow-up: Fear of syphilis. Tested RPR positive during pregnancy. Have high vitamin D1 level. Related to Lyme disease? 2 hours later
Thank you for your answer. Some sites i read tell of those tests being less effective in late syphills And that is my concern that it wasn't picked up. Do you have any information on the increases levels of d 1, 25 dihydroxy test?
Answered by Dr. Ram Choudhary 24 hours later
Welcome back to Healthcare Magic!
The tests have fair sensitivity and specificity even in late course.
In extremely late course where disease is in waning out it may have less sensitivity but before that the patient would have apparently many symptoms which is not the case with you.
The causes for raised levels of vit.D in blood are many and unrelated to the occurrence of syphylis, can be related to excess input of the suppliments as well if you are having any.
I hope that answers your query.
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to

The user accepted the expert's answer

Ask an Internal Med Specialist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor