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FBS was 241 and HBA1C was 9.8, reduced medication. FBS was 126 and PLBS was 90. Continue Metmorfin? FBS is high and PLBS is normal?

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Hello Doctor,
My BS was 241 and HBA1C was 9.8, after medication in cosultation with the doctor, my BS is under control now, after gradually reducing the medication asper doctor, my FBS was 126 and PLBS was 90, my doctor asked me to continue with Metmorfin 250MG 1/2 tab.

My question is why my FBS is high and PLBS is normal?
Posted Thu, 4 Jul 2013 in Diabetes
Answered by Dr. Basheer Ahamed 2 hours later

Welcome to XXXXXXX Thanks for your query.

At the outset I felt happy for you because you have effectively controlled your blood sugar.

You're concerned that your Fasting blood sugar is higher than your Postprandial blood sugar.

I'm mentioning some of the reasons for increased FBS below for your easy understanding.

1. Prediabetic.

In Prediabetes the first thing to get affected is the fast blood sugar level.
It is called impaired fasting glucose. Here the Postprandial blood sugar will be normal and the fasting will be high. ie 100 mg/dl to 126 mg/dl.

2. Increased insulin resistance.

In this case the body(muscle and fat cells) are not able to utilise the insulin for effective glucose synthesis. This increases the fasting glucose.

In your case this may be the reason.
Metformin is an insulin sensitizer. It sensitizes the muscle and fat cells to utilize insulin for the synthesis of glucose.
With the help of metformin alone you're control your blood sugar effectively.
In my opinion if the dose of metformin is increase to 500 mg Sustained release than your fasting will be controlled.

3. Hormonal.

Naturally there is an increased amount of cortisol in our body in the early hours of the day and it increases the Fasting blood sugar.

4. Liver.

Liver has large amount of glucose in it. When a person is not taking food like at night it releases glucose into the person's blood. In normal individual more insulin is secreted to control the blood sugar.
But in a Diabetic due to insulin deficiency the blood sugar rises. So the Fasting blood sugar raises.

Just a word of advice.

For sustained blood sugar control Diet, exercise, weight reduction and regular medication are all needed.

Hope I have answered your query.
Pleased to answer other queries.
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