HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Does Vitamin C Interact With Allopurinol?

default
Posted on Tue, 15 Nov 2016
Question: Why should I avoid vitaminC when using allopurinol?
doctor
Answered by Dr. Scott Rebich (45 minutes later)
Brief Answer:
Increase risk of kidney stones

Detailed Answer:
Hi there,

You should avoid Vitamin C when using allopurinol because the combination of the two medications will significantly increase your risk of developing a kidney stone. However, this may only be demonstrated in people who are taking large amounts (>500 mg daily) of vitamin C.

I would recommend stopping the Vitamin C to decrease your risk of kidney stones. Allopurinol is a much better drug for the treatment of gout anyways. Actually, vitamin C was shown to have no effect on decreasing uric acid levels with and without allopurinol, and therefore, it is clinically ineffective in the treatment in gout.

There is some new research that demonstrates that vitamin C might reduce your risk of getting gout, but it has not effect on the treatment.

I hope this helps!
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Scott Rebich

Internal Medicine Specialist

Practicing since :2015

Answered : 283 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Does Vitamin C Interact With Allopurinol?

Brief Answer: Increase risk of kidney stones Detailed Answer: Hi there, You should avoid Vitamin C when using allopurinol because the combination of the two medications will significantly increase your risk of developing a kidney stone. However, this may only be demonstrated in people who are taking large amounts (>500 mg daily) of vitamin C. I would recommend stopping the Vitamin C to decrease your risk of kidney stones. Allopurinol is a much better drug for the treatment of gout anyways. Actually, vitamin C was shown to have no effect on decreasing uric acid levels with and without allopurinol, and therefore, it is clinically ineffective in the treatment in gout. There is some new research that demonstrates that vitamin C might reduce your risk of getting gout, but it has not effect on the treatment. I hope this helps!