HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Does Radiation In Large Amount Can Cause Polarization And Depolarization In Cell?

default
Posted on Tue, 31 Mar 2015
Question: My question is on the effects of Beta and/or gamma particles through out certain regions of the brain, possibly causing tingling and discomfort among the dendrites of the cerebral cortex, I've heard about Calcium molecules being responsible for communication between neurons, but how would the channels react exposed to those irradiated particles? I believe I've struggled with some sort of aphasia.
doctor
Answered by Dr. Vivek Chail (6 hours later)
Brief Answer:
Radiation in large amount can cause polarization and depolarization in cell

Detailed Answer:
Hi XXXX,
Thanks for writing in to us.

I have read your query in detail.
Please find my observations below.

1. You need a high dose of radiation to affect the neurons. Point doses of 72 Gy are associated with a 5% risk of radiation necrosis. This is dose depended effect.

2. Altered neurocognitive brain function, particularly memory is a sign of radiatiation effect on the brain.

3. Communication between neurons is complicated and involves sodium, calcium and potassium channels. The neurons also communicate with each other through electrical impulses. Radiation can cause various levels of neuronal excitation resulting form polarization or depolarization of the ion gated channels.

4. Beta and gamma particles specifically will not cause aphasia unless a large amount of radiation is given to the speech center as in patients getting treated for brain tumor.

Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Vivek Chail

Radiologist

Practicing since :2002

Answered : 6874 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Does Radiation In Large Amount Can Cause Polarization And Depolarization In Cell?

Brief Answer: Radiation in large amount can cause polarization and depolarization in cell Detailed Answer: Hi XXXX, Thanks for writing in to us. I have read your query in detail. Please find my observations below. 1. You need a high dose of radiation to affect the neurons. Point doses of 72 Gy are associated with a 5% risk of radiation necrosis. This is dose depended effect. 2. Altered neurocognitive brain function, particularly memory is a sign of radiatiation effect on the brain. 3. Communication between neurons is complicated and involves sodium, calcium and potassium channels. The neurons also communicate with each other through electrical impulses. Radiation can cause various levels of neuronal excitation resulting form polarization or depolarization of the ion gated channels. 4. Beta and gamma particles specifically will not cause aphasia unless a large amount of radiation is given to the speech center as in patients getting treated for brain tumor. Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements. Hope your query is answered. Do write back if you have any doubts. Regards, Dr.Vivek