Does proton pump inhibitors cause PVCs?
My answer as follows:
Welcome back again on HCM!
Regarding your concern, I would explain that there is not a direct conection between PPI and PVCs.
They are not known to cause this adverse effect.
From the other hand, considering your clinical situation, I do not think that your PVCs are related to your stomach.
As your symptoms are triggered by physical activity or standing up, an orthostatic intolerance should be suspected.
I recommend measuring your blood pressure and heart rate in sitting and then after 5minutes of standing position. If your blood pressure falls more than 20mmHg in standing up position compared with sitting position, it may indicate possible orthostatic hypotension. If your heart rate increases more than 30bpm in standing up position compared to sitting position, it could indicate postural tachycardia.
Postprandial hypotension with reflex tachycardia is part of this syndrome (which could explain why you feel worse after eating).
A Head Up Tilt test would be necessary to rule in/out these possible disorder.
I would also recommend checking your thyroid hormone levels and cortisol plasma levels for possible thyroid or adrenal gland disorder, which could trigger this symptomatology.
You should discuss with your doctor on the above issues.
Hope to have been helpful!
If you have any other question, do not hesitate to ask me!
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