Does myasthenia gravis associated thymomas spread to other parts of body?
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Please find my observations below.
1. Myasthenia gravis is a disorder in which usually there is an antibody which develops against the acetylcholine receptors. Acetylcholine is a neurotransmitter and helps in muscle contractions due to activation of receptors. In myasthenia gravis the receptors are blocked by the antibodies. This is an autoimmune condition.
2. Thymus is an organ in the front upper chest which participates in the development of immune system. It is larger in children and slowly reduces in size in adults. Thymus has been seen to become slightly enlarged in 15 percent of myasthenia gravis patients and forms a thymoma.
3. Myasthenia gravis associated thymomas are of a particular cortical type and have the capacity to propagate the maturation of immature naive CD4 T cells and export mature naive T cells into the periphery. It is usually not cancerous enough to spread to other areas but requires histopathological evaluation. Your thymoma being encapsulated is classified as stage I disease and is most common. There are rare chances of recurrence and you might be suggested to get follow up CT scan done after 2 years or as suggested by your doctor. This is to make sure there is no recurrence. Aggressive treatment is required in case of invasive thymoma and your doctor will tell you if your test results suggest additional treatment.
4. The thymoma is probably closely related to your myasthenia gravis and as mentioned above 15 percent of myasthenia gravis patients will have a thymoma. Treatment is surgical excision.
5. Since the thymoma was instructing the lymph tissue elsewhere to behave in a certain way, its removal makes you feel the difference.
Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.
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