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Does intake of Trajenta lead to low blood pressure?

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Posted on Sat, 16 Apr 2016
Question: I have recently had nigh and low BP and friblilation of the heart. Also have type 2 diabetes.I am taking Avapro HCT 300 dose 12.5 mg,
Diabex 1000, Xarelto 20 mg, glucobay 50mg x3 times before meals, have recently stopped taking glyade 30mg and am now have started trajenta 5 mg, my BP has dropped to below 100/ 70 and pulse 84. Does trajenta effect BP ??
thank you, XXXX
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Answered by Dr. Prof. Kunal Saha (1 hour later)
Brief Answer:
Trajenta is unlikely to have caused your blood pressure to drop.

Detailed Answer:
Thanks for asking on HealthcareMagic.

Trajenta (linagliptin) is a medicine used in the treatment of type 2 diabetes mellitus. It works by blocking the breakdown of ‘incretin’ hormones in the body. These hormones are released after a meal and stimulate the pancreas to produce insulin. By prolonging the action of incretin hormones in the blood, linagliptin stimulates the pancreas to produce more insulin when blood glucose levels are high. Linagliptin does not work when the blood glucose is low. Linagliptin also reduces the amount of glucose made by the liver, by increasing insulin levels and decreasing the levels of the hormone glucagon. Together, these processes reduce blood glucose levels and help to control type-2 diabetes. There are several studies that have demonstrated no correlation between this medicine and the lowering of blood pressure. In other words, Trajenta is unlikely to have caused your blood pressure to drop.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Prof. Kunal Saha

General & Family Physician

Practicing since :1954

Answered : 4467 Questions

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Does intake of Trajenta lead to low blood pressure?

Brief Answer: Trajenta is unlikely to have caused your blood pressure to drop. Detailed Answer: Thanks for asking on HealthcareMagic. Trajenta (linagliptin) is a medicine used in the treatment of type 2 diabetes mellitus. It works by blocking the breakdown of ‘incretin’ hormones in the body. These hormones are released after a meal and stimulate the pancreas to produce insulin. By prolonging the action of incretin hormones in the blood, linagliptin stimulates the pancreas to produce more insulin when blood glucose levels are high. Linagliptin does not work when the blood glucose is low. Linagliptin also reduces the amount of glucose made by the liver, by increasing insulin levels and decreasing the levels of the hormone glucagon. Together, these processes reduce blood glucose levels and help to control type-2 diabetes. There are several studies that have demonstrated no correlation between this medicine and the lowering of blood pressure. In other words, Trajenta is unlikely to have caused your blood pressure to drop. Regards