Brief Answer:
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Detailed Answer:
Hello XXXXXXX
Thank you for writing to us with your health concern.
I would be glad to assist you with your doubts.
Let me answer your questions in the order in which you have asked them -
1. Progynova contains estrogen, and Duphaston contains
progesterone. Once ovulation has occurred, you have high chances of conception. In case pregnancy gets confirmed, then these two hormones will support the growing pregnancy. Women with irregular cycles often have deficiency of progesterone, so it is often prescribed. Estrogen will increase the blood flow to the uterine lining, which also will help the fertilized egg to get implanted inside the uterus. So do not worry, both the hormones are given for pregnancy support.
2. If you get pregnant during the Progynova course, it will not harm the baby at all, it will only support the growing pregnancy.
3. The treatment protocol is perfectly correct. Since you have been trying to conceive since one year, some help is obviously required. I hope a thorough investigation for irregular cycles has been conducted. I suspect that you would be suffering from
Polycystic Ovarian Syndrome - for that you need to have complete hormonal assessment - FSH, LH, prolactin, DHEAS, free testosterone, oral
glucose tolerance test, fasting serum insulin . You would have been given Siphene if ovulation problems were suspected.
4. With Siphene, more than 50 % of women ovulate, and around 5 - 20 % achieve conception. If you fail to conceive with 3 - 6 cycles of Siphene stimulation, then you should go for assessment of
fallopian tube patency ( via laparoscopy ).
5. Taking just 10 days of Progynova will not increase your risk of any of the conditions.
Breast cancer, cardiovascular complications and stroke are complications that might occur only in very few users, and that too after prolonged use , for many years.
6. Progynova is commonly given to women having difficulty in conception, so do not be apprehensive.
7. As I said, once detailed investigation for polycystic ovarian syndrome has been done,
semen analysis is normal, then you can go for 3 - 6 cycles more of siphene treatment with follicular monitoring. If this fails go for laparoscopy to assess whether your tubes are open. If tubes are blocked or no response to siphene / gonadotropin injections are achieved, then IVF (
in vitro fertilization ) should be considered. You can combine IUI ( intra uterine insemination ) with the siphene treatment cycles, it will improve chances of pregnancy.
8. As only one follicle was seen, there are no chances of multiple pregnancy in your case.
With polycystic ovarian syndrome and clomiphene treatment, very very rarely some follicle might ovulate later on in the cycle also, but this is extremely rare, so if you conceive, in your case , in this cycle, chances of multiple pregnancy are very low.
Do not stress out, your treatment is on the right track, just take regular folic acid supplements also, and keep your weight in check.
You are young, and I am sure you will achieve pregnancy pretty soon.
All the best.
Please feel free to ask for further clarifications.
Take care