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Does a tumor on adrenal gland produce high cortisol levels?

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Posted on Mon, 28 Jul 2014
Question: Does a tumor on adreanl gland that produced to much testosterone produce cortisol as well? Does it produce ecery hormone or just that specific hormone?
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Answered by Dr. Binu Parameswaran Pillai (13 hours later)
Brief Answer:
Benign tumour produce specefic hormone

Detailed Answer:
Good day,

Adrenal gland has a portion called cortex and another portion called medulla.
Cortex produce hormones like cortisol, androgens and aldosterone.

Medulla produce adrenaline and nor adrenaline.
Usually a benign tumor produce a specific hormone. If the benign tumor is arising from cortisol producing cells, it will secrete cortisol only.

However, malignant tumors produce more than one hormone

Regards
Binu
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Binu Parameswaran Pillai (2 hours later)
So if the tumor is producing testosterone does it automatically produce cortisol or just testosterone?
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Answered by Dr. Binu Parameswaran Pillai (16 minutes later)
Brief Answer:
Hi

Detailed Answer:

Usually yes. But as i mentioned earlier, malignant tumours can produce both. However, an ACTH producing tumour of pituitary can stimulate adrenal gland and both cortisol and androgens can go high.



Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Binu Parameswaran Pillai (12 hours later)
So a benign tumor that produced testosterone will also produce cortisol?
What does to much cortisol do to brain?
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Answered by Dr. Binu Parameswaran Pillai (1 hour later)
Brief Answer:
Hi

Detailed Answer:
Hello,
Benign tumour that produce testosterone usually do not produce cortisol.

Excess cortisol secretion cause cushing's syndrome. Excess cortisol can affect brain and cause emotional disturbances, Euphoria, Depression as well as psychosis. But these are rare. Excess cortisol can cause obesity, high blood pressure, high blood sugarss, weak bones and musceles, fractures of bones etc. These are more common than effects on brain.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Binu Parameswaran Pillai

Endocrinologist

Practicing since :2003

Answered : 1435 Questions

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Does a tumor on adrenal gland produce high cortisol levels?

Brief Answer: Benign tumour produce specefic hormone Detailed Answer: Good day, Adrenal gland has a portion called cortex and another portion called medulla. Cortex produce hormones like cortisol, androgens and aldosterone. Medulla produce adrenaline and nor adrenaline. Usually a benign tumor produce a specific hormone. If the benign tumor is arising from cortisol producing cells, it will secrete cortisol only. However, malignant tumors produce more than one hormone Regards Binu