Brief Answer:
Of the 4 medications listed Klonopin most likely to cause symptoms

Detailed Answer:
Good afternoon.

Of the 4 medications you've listed the one BY ITSELF that would most likely cause any given individual to suffer from slurred speech and confusion would be Klonopin because it is a benzodiazepine with primary effects on the central nervous system probably to a much greater extent that the other drugs.

If on the other hand you have been taking the Klonopin for some time along with the other medications and Zofran was the one added to the mix then, if we were blame any of the drugs in your list it would probably have to be the Zofran. The Linzess is interesting because studies on INTERACTIONS with other drugs have not been performed on this agent nor does it significantly interact with any of the liver enzyme systems to cause reduction in metabolism of any of the other drugs.

Therefore, in answer to your question....so long as none of the other drugs you initially have been taken have had any changes to their doses or dosing frequencies and if Zofran were the newest medication added to the mix and shortly after taking it there was slurring of speech and confusion then, this would be the most likely suspect. Having said that if in addition to the symptoms you mention if there is involvement of any limb such as an arm, leg, or even portion of the face that seems to have weakened on one side compared to the other then, please see an emergency room doctor right away because then, this is no longer in the realm of a medication side effect.

In the alternative the symptoms should resolve or improve with time and/or discontinuation of the Zofran. Ask your physician for a substitute drug as soon as is feasible.

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This query has utilized a total of 15 minutes of professional time in research, review, and synthesis for the purpose of formulating a return statement.

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Brief Answer:
I think it depends on what you mean by SLURRED SPEECH & CONFUSION

Detailed Answer:
Your offer of new information makes me wonder as to what you may mean when you use the terms SLURRED SPEECH and CONFUSION. When patients have "headcolds" they typically don't feel well with malaise, lethargy, and fatigue. If they take OTC medications that contain other chemicals in them such as antihistamines, pseudoepherine, melatonin, and other ingredients it certainly is conceivable that a person could become a little groggy and slowed down. Depending upon how much...perhaps, one could imagine CONFUSION with slurred speech....but again, the jist of your question and how you presented the initial information made me think more of medication side effects and/or interactions.

Once again, if the additional information I've provided has been helpful in answering your questions can you do me the favor of CLOSING THE QUERY and include some fine words of feedback along with a 5 STAR rating? Please let me know how things turn out.

Do not forget to contact me in the future at: www.bit.ly/drdariushsaghafi for additional questions, comments, or concerns having to do with this topic or others.

This query has utilized a total of 24 minutes of professional time in research, review, and synthesis for the purpose of formulating a return statement.

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