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Does Vyvanse Interact With Hydrocodone?

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Posted on Sat, 23 Sep 2017
Question: I took Vyvanse at about 11am. It's 1:25am now. I have a killer migraine. I have hydrocodone 7.5/325. Is this likely a safe scenario? The Vyvanse is not entirely out of my system, but obviously it's been some time since I took it.
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Answered by Dr. salah saad shoman (1 hour later)
Brief Answer:
Moderate interaction

Detailed Answer:
Dear Sir, I have gone through your question and I understand your concerns . Vyvanse and hydrocodone has no reported interactions between each other but both can cause the side effects of elevated blood pressure and increased heart rate. since Vyvanse will not be excreted from your system until six hours from administration , then I would recommend that you use hydrocodone with caution.. If you experience palpitations or severe headache then you should monitor your heart rate and blood pressure level .
Alcohol should be avoided while using both medications.. I hope you find this helpful ..
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Kampana
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Answered by
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Dr. salah saad shoman

Internal Medicine Specialist

Practicing since :2004

Answered : 3153 Questions

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Does Vyvanse Interact With Hydrocodone?

Brief Answer: Moderate interaction Detailed Answer: Dear Sir, I have gone through your question and I understand your concerns . Vyvanse and hydrocodone has no reported interactions between each other but both can cause the side effects of elevated blood pressure and increased heart rate. since Vyvanse will not be excreted from your system until six hours from administration , then I would recommend that you use hydrocodone with caution.. If you experience palpitations or severe headache then you should monitor your heart rate and blood pressure level . Alcohol should be avoided while using both medications.. I hope you find this helpful ..