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Does THC Interact With Guanfacine?

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Posted on Fri, 13 Jan 2017
Question: can mixing thc and guanfacine cause an adverse reaction such as serotonin syndrome?

I ate a marijuana edible 2 days ago and had a very strong reaction. I am now feeling like I am having panic attacks and I feel totally out of it.
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (38 minutes later)
Brief Answer:
Serotonin syndrome is not known complication of THC with guanfacine

Detailed Answer:
Hello,
Thanks for using Healthcaremagic.

I read your query and understand your concerns.

Marijhuana is known to cause variety of effects and panic reaction is one among them. In my clinical experience I have observed effects such as severe anxiety, panic attacks, psychosis, paranoia and many others even after single use of THC and I completely agree that you have developed strong reaction following marijhuana use.

Having said this I like to inform that THC is not associated with any incidence of serotonin syndrome irrespective of presence of guanfacine or not.

The absence of serotonin syndrome does not mean that you will mix them as mixing psychoactive substance sometime cause effects which can not be explained on the basis of combination of use. In other words there are some synergistic effects which can occur when two or more substances of abuse combined.

I hope this helps you.
If you have any further query, I would be glad to help you.
If not, you may close the discussion and if possible you may rate the answer for my future patients.
In future if you wish to contact me directly, you can use the below mentioned link:
http://doctor.healthcaremagic.com/doctors/dr-ashok-kumar/67386
Thanks and regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Ashok Kumar Choudhary (2 minutes later)
will the effects wear off?
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (3 minutes later)
Brief Answer:
Yes if there is no more exposure

Detailed Answer:
Hello,
Thanks for reverting back to me.

The most effects of cannabis last only for days and never cross the month provided there is no further intake. In case there is repeated intake it can cause permanent damage to the brain.


I mean to say that there are high chances that effects will be reverted back but there should not be further exposure to it.

I hope this helps you further.
Thanks and regards.
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Ashok Kumar Choudhary

Psychiatrist

Practicing since :2000

Answered : 3354 Questions

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Does THC Interact With Guanfacine?

Brief Answer: Serotonin syndrome is not known complication of THC with guanfacine Detailed Answer: Hello, Thanks for using Healthcaremagic. I read your query and understand your concerns. Marijhuana is known to cause variety of effects and panic reaction is one among them. In my clinical experience I have observed effects such as severe anxiety, panic attacks, psychosis, paranoia and many others even after single use of THC and I completely agree that you have developed strong reaction following marijhuana use. Having said this I like to inform that THC is not associated with any incidence of serotonin syndrome irrespective of presence of guanfacine or not. The absence of serotonin syndrome does not mean that you will mix them as mixing psychoactive substance sometime cause effects which can not be explained on the basis of combination of use. In other words there are some synergistic effects which can occur when two or more substances of abuse combined. I hope this helps you. If you have any further query, I would be glad to help you. If not, you may close the discussion and if possible you may rate the answer for my future patients. In future if you wish to contact me directly, you can use the below mentioned link: http://doctor.healthcaremagic.com/doctors/dr-ashok-kumar/67386 Thanks and regards.