Does TBI aggravate seizures?
Detailed answer below.
Hello and thanks for the direct question.
I have read your question and understand your concerns.
The way that TBI aggravates seizures is related to blood supply of the brain.
Seizures arise from small brain areas with disfunctional brain tissue ( scar tissue, hippocampal sclerosis eg.), when other organic cause is excluded ( vessels malformation, tumors).
These areas most probably are result of low oxygen supply.
TBI worsens the oxygen supply of the brain, affecting thus those scar tissue areas and spreading them.
Another possibility of TBI worsening seizures is creating by direct damage new areas of seizures activity ( brain contusion, hematomas).
In the other hand, a brain that has suffered from seizures is more susceptible to damage from different factors including TBI.
Seizures alter the electric brain activity and in case of seizures there are increased demands of brain for oxygen and glucose.
TBI alters and increases brain demand too, so the result is a brain more prone to damage.
If the seizures aggravated are previous ones or new ones, this needs confirmation by clinical and functional ( EEG ) study compared to ones before the TBI.
About treatment, Levetiracetam (Keppra) is a relatively new option in controlling seizures with less side effects than old seizures treatment drugs.
This possibility needs to be discussed with your Neurologist.
Hope I helped you. Best regards.