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Does Ropinirole Or Sinemet Causes Atrial Fibrillation And Arrhythmic Events?
Question: I am being monitored for attrial fibrillation. I suspect it was
triggered by an increase in either ropinerole or sinemet because my
neurologist was trying to decrease my off times due to Parkinsonism. My
pulse rate dropped to 42 a week ago and my cardiologist took me off from
Coreg, the action which restored my pulse to 60 or 61. I'd love to know
if my suspicions are correct before we change any more dosages.
My previous case no. was HCM145823. I have not pursued any options
regarding that question due to the distractions of my heart.
I think I am taking too many medicines already. Maybe my several drs
need to meet and decide what is the best treatment to cover my many
ailments. At my age (76) , I can understand a baby aspirin to ward off a
stroke and some CoQ 10 to keep things young and flexible, some calcium
with vitamin D, fish oil, and a couple of prescriptions for things not
necessarily connected to aging should be more than enough to keep me
happy , healthy,and sane for my progeny.
triggered by an increase in either ropinerole or sinemet because my
neurologist was trying to decrease my off times due to Parkinsonism. My
pulse rate dropped to 42 a week ago and my cardiologist took me off from
Coreg, the action which restored my pulse to 60 or 61. I'd love to know
if my suspicions are correct before we change any more dosages.
My previous case no. was HCM145823. I have not pursued any options
regarding that question due to the distractions of my heart.
I think I am taking too many medicines already. Maybe my several drs
need to meet and decide what is the best treatment to cover my many
ailments. At my age (76) , I can understand a baby aspirin to ward off a
stroke and some CoQ 10 to keep things young and flexible, some calcium
with vitamin D, fish oil, and a couple of prescriptions for things not
necessarily connected to aging should be more than enough to keep me
happy , healthy,and sane for my progeny.
Brief Answer:
I would recommend as follows:
Detailed Answer:
Hello!
Welcome and thank you for asking on HCM!
Regarding your concern, I would like to explain that your suspicions are right.
Ropinirole and Sinemet are dopamine agonists, and as such they have the potential to trigger hypertension, palpitations, extrasystoles, tachycardia, and also more complex arrhythmic events.
It is for this reason, that when deciding to uptitrate their doses, a close hemodynamic monitoring is necessary.
Regarding that pulse rate drop a week ago (42 bpm), it doesn't seem to be related to Parkinson medications.
Parkinson disease is frequently expressed with important alterations in the autonomic nervous system, which may lead to orthostatic hypotension, sometimes in bradycardia and dysrrhythmias.
From the other side other degenerative cardiac conduction system disorders should be sought (as they become more frequent with age).
I recommend you to be in close contacts with your attending neurologist and cardiologist, as a careful differential diagnosis should be made between, a possible underlying heart disorder, adverse therapeutic effects of Parkinson disease therapy, and Parkinson disease implications itself.
Hope to have been helpful to you!
Feel free to ask me whenever you need! Greetings! Dr. Iliri
I would recommend as follows:
Detailed Answer:
Hello!
Welcome and thank you for asking on HCM!
Regarding your concern, I would like to explain that your suspicions are right.
Ropinirole and Sinemet are dopamine agonists, and as such they have the potential to trigger hypertension, palpitations, extrasystoles, tachycardia, and also more complex arrhythmic events.
It is for this reason, that when deciding to uptitrate their doses, a close hemodynamic monitoring is necessary.
Regarding that pulse rate drop a week ago (42 bpm), it doesn't seem to be related to Parkinson medications.
Parkinson disease is frequently expressed with important alterations in the autonomic nervous system, which may lead to orthostatic hypotension, sometimes in bradycardia and dysrrhythmias.
From the other side other degenerative cardiac conduction system disorders should be sought (as they become more frequent with age).
I recommend you to be in close contacts with your attending neurologist and cardiologist, as a careful differential diagnosis should be made between, a possible underlying heart disorder, adverse therapeutic effects of Parkinson disease therapy, and Parkinson disease implications itself.
Hope to have been helpful to you!
Feel free to ask me whenever you need! Greetings! Dr. Iliri
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
What does this mean ?
a close hemodynamic monitoklopmk,jring is necessary.+
Brief Answer:
Explanation as follows:
Detailed Answer:
Hi again!
"a close hemodynamic monitoring is necessary" means that it is important to monitor very closely (frequently) the blood pressure and heart rate to better avoid any possible adverse medication effects.
If you have further uncertainties, do not hesitate to contact me directly!
Best regards,
Dr. Iliri
Explanation as follows:
Detailed Answer:
Hi again!
"a close hemodynamic monitoring is necessary" means that it is important to monitor very closely (frequently) the blood pressure and heart rate to better avoid any possible adverse medication effects.
If you have further uncertainties, do not hesitate to contact me directly!
Best regards,
Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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