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Does Paroxetine Increase The Risks Of Birth Defects In A Foetus?

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Posted on Tue, 18 Oct 2016
Question: What are the consequences of taking following medicines on pregnancy 1 pexep credit 25 1hs 2 lamitor 50mg 1 0 2 & zapiz 0.5mg sos
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Answered by Dr. Seikhoo Bishnoi (27 minutes later)
Brief Answer:
Paroxetine can increase risk of birth defects

Detailed Answer:
Hello thanks for asking from HCM for your health related queries

I can understand your concern. Paxep is Paroxetine and is a SSRI drug. The drug should be preferably avoided in pregnancy especially during first trimester. The drug can increase risk of birth defects mainly congenital heart defects, persistent pulmonary hypertension, autism, mental retardation in developing foetus. If SSRIs are needed then Sertraline is considered as safest out of all SSRIs in pregnancy.

Lamitor is considered as relatively safer in pregnancy and can be given as per prescription.

Zapiz too in SOS basis will not cause any serious adverse effects, no need to worry.

Thanks, Take care


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Seikhoo Bishnoi (8 hours later)
Doctor I am asking this for my daughter who has gone to her in laws at XXXXXXX She is suspecting pregnancy. Now she has informed that besides above, she has also been prescribed Bupron.xl 300mg 1hs and qutipin 12.5mg 1od.please also advise for these medicines and their alternativesite to ensure safe pregnancy. Her doctor has told that all these medicinesites are pregnancy proof .with regards
doctor
Answered by Dr. Seikhoo Bishnoi (7 hours later)
Brief Answer:
Sertraline is considered as safest in pregnancy.

Detailed Answer:
Hello thanks for asking again

These drugs are not safe in pregnancy, though risk-benefit is judged by psychiatrists. For depressive symptoms ask her to consult a psychiatrist. Quetipin at 12.5 mg will not cause much effects on developing foetus and will help in sleep. Bupropion too should be avoided.

Drugs like Sertraline can be used. Sertraline is considered as safest of all antidepressants for use in pregnancy. Please talk to her doctor and ask for prescription of the drug. With time her depression will improve.

Thanks. Take care
Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
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Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

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Does Paroxetine Increase The Risks Of Birth Defects In A Foetus?

Brief Answer: Paroxetine can increase risk of birth defects Detailed Answer: Hello thanks for asking from HCM for your health related queries I can understand your concern. Paxep is Paroxetine and is a SSRI drug. The drug should be preferably avoided in pregnancy especially during first trimester. The drug can increase risk of birth defects mainly congenital heart defects, persistent pulmonary hypertension, autism, mental retardation in developing foetus. If SSRIs are needed then Sertraline is considered as safest out of all SSRIs in pregnancy. Lamitor is considered as relatively safer in pregnancy and can be given as per prescription. Zapiz too in SOS basis will not cause any serious adverse effects, no need to worry. Thanks, Take care