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Does Nitrostat lower BP?

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Posted on Mon, 23 Jun 2014
Question: Does Nitrostat lower BP and if so by how much and for how long if only one does of .4mg is taken?
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Answered by Dr. Shoaib Khan (1 hour later)
Brief Answer:
Can lower BP; cannot say how much; few minutes

Detailed Answer:
Hello sir and welcome.

Thank you for writing to us.

Nitrostat contains the active ingredient nitroglycerin which has an effect on blood vessels resulting in their dilation.

The main purpose of this medication is in the use of treatment of angina (chest pain) and in the prevention of cardiac events. By dilating the blood vessels this medication reduces the flow of blood, thus reducing the pressure on the heart, which in turn helps it relax and prevents major cardiac events (eg. myocardial infarction).

I would not say this medication is used to treat blood pressure, but it does reduce the blood pressure to a certain extent, say 10-20 mm Hg (systolic or diastolic). This is only an approximate estimation, and can very easily vary from person to person and from one circumstance to another.

As for the elimination and effect of this drug; it is very quickly eliminated from the body, staying in the body for only a few minutes (not even an hour). Its peak value is reached at about 6-7 minutes, and from there the concentration of the medication gradually drops and completely stops within the hour.

So the effect of the medication, whether on the heart or blood pressure would last only a few minutes with one dose of 0.4 mg.

I hope I have successfully addressed your queries sir. Please feel free to write back to me for any further clarifications, I would be more than happy to help you.

Best wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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Does Nitrostat lower BP?

Brief Answer: Can lower BP; cannot say how much; few minutes Detailed Answer: Hello sir and welcome. Thank you for writing to us. Nitrostat contains the active ingredient nitroglycerin which has an effect on blood vessels resulting in their dilation. The main purpose of this medication is in the use of treatment of angina (chest pain) and in the prevention of cardiac events. By dilating the blood vessels this medication reduces the flow of blood, thus reducing the pressure on the heart, which in turn helps it relax and prevents major cardiac events (eg. myocardial infarction). I would not say this medication is used to treat blood pressure, but it does reduce the blood pressure to a certain extent, say 10-20 mm Hg (systolic or diastolic). This is only an approximate estimation, and can very easily vary from person to person and from one circumstance to another. As for the elimination and effect of this drug; it is very quickly eliminated from the body, staying in the body for only a few minutes (not even an hour). Its peak value is reached at about 6-7 minutes, and from there the concentration of the medication gradually drops and completely stops within the hour. So the effect of the medication, whether on the heart or blood pressure would last only a few minutes with one dose of 0.4 mg. I hope I have successfully addressed your queries sir. Please feel free to write back to me for any further clarifications, I would be more than happy to help you. Best wishes.