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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Metolazone cause severe itching and how should the itching be stopped?

Answered by
Dr. Ivo Ditah

Internal Medicine Specialist

Practicing since :2002

Answered : 3914 Questions

Posted on Thu, 6 Dec 2018 in Medicines and Side Effects
Question: does metolazone 5mg cause severe itching. I have been gaining weight ( and if so, how do you combat it? I need the drug to combat my fluid retention( 25 lbs in last three days) I also take Bumetanide as well as hydrocloralthyazide?
Answered by Dr. Ivo Ditah 25 minutes later
Brief Answer:

Yes, pruritus is a known side effect of Metolazone.

Detailed Answer:


Severe itching is a side effect of Metolazone.

With you gaining more than 30 pounds in 3 days clearly means your water pills are not enough.

I will recommend we switch to more potent pills. The most potent water pills are Lasilix. I will suggest you contact your cardiologist as soon as possible to get this sorted.

In all, stop this drug. Get your water pills adjusted. I recommend Lasix coming on board.

In addition, reduce salt intake and drink less. Monitor your urination as well, hopefully the kidneys are working good.

I hope this helps and guides.

I wish you well.


Dr. Ivo Ditah,
Internal Medicine Specialist
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

The User accepted the expert's answer

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