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Does Imodium Cause False Positive Test Results For Opiates?

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Posted on Tue, 14 Jun 2016
Question: Does Immodium cause a false positive for opiates on a cotton swab employer drug screen?
doctor
Answered by Dr. Shoaib Khan (1 hour later)
Brief Answer:
It should not as there is no relation with opiates whatsoever

Detailed Answer:
Hello sir and welcome.

Thank you for writing to us.

I have gone through your query with diligence and would like you to know that I am here to help. Imodium (with the active ingredients loperamide) is an anti-diarrheal medication and not in any way a metabolite of any opiates. Drug screening tests that test for opiate look for morphine in the test result, and in no way would imodium (loperamide) test positive for this.

If at all you were on only this medication and your test returned a positive result, then this was a false-positive and I would recommend a mass spectrometry based method which would be most accurate. But even still, declare the imodium on the UDS, this will make things more simpler.

I hope you find my response helpful and informative. Please feel free to write back to me for any further clarifications, I am always here to help.

Best wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Shoaib Khan (1 hour later)
The concern would be that it is chemically similar to opiates, although it of course doesn't not have psychoactive effects. I suppose if the test were for morphine specifically, it is not a concern. Any thoughts?
doctor
Answered by Dr. Shoaib Khan (8 hours later)
Brief Answer:
It usually is sir, but either way declare imodium in the form

Detailed Answer:
Hello once again.

The tests look for opiates with mostly morphine as the target drug, and anything similar around it. Rest assured, if the test is conducted by an experienced laboratory and skilled personnel, it shouldn't result in a false-positive. As explained earlier sir, they should provide you with a declaration form before the test, wherein you can mention what medications and/or drugs you have taken lately, therein, mention imodium (loperamide) and the sample provided by you should be tested to exclude any similarities or discrepancies caused by the drug imodium.

Hope this helps sir.

Best wishes. :)
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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Does Imodium Cause False Positive Test Results For Opiates?

Brief Answer: It should not as there is no relation with opiates whatsoever Detailed Answer: Hello sir and welcome. Thank you for writing to us. I have gone through your query with diligence and would like you to know that I am here to help. Imodium (with the active ingredients loperamide) is an anti-diarrheal medication and not in any way a metabolite of any opiates. Drug screening tests that test for opiate look for morphine in the test result, and in no way would imodium (loperamide) test positive for this. If at all you were on only this medication and your test returned a positive result, then this was a false-positive and I would recommend a mass spectrometry based method which would be most accurate. But even still, declare the imodium on the UDS, this will make things more simpler. I hope you find my response helpful and informative. Please feel free to write back to me for any further clarifications, I am always here to help. Best wishes.