Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

163 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Does Effexor interact with Sertraline?

Answered by
Dr. Alexander H. Sheppe


Practicing since :2014

Answered : 2243 Questions

Posted on Fri, 3 Mar 2017 in Mental Health
Question: Hi my name is xxxxxxx.
I'm in XXXXXXX and ran out of Effexor 150mg and feel like I have vertigo, I've been off of it for 3 days. I happen to have some sertraline on me 100mg because I was on it 1 year ago, should I take that to help with these symptoms?
Answered by Dr. Alexander H. Sheppe 2 hours later
Brief Answer:

Detailed Answer:
Hello, and thanks for your question.

What you are experiencing is antidepressant withdrawal. As you are experiencing, this is uncomfortable, but is not dangerous, and will resolve within the next 48 hours. Do not take sertraline 100mg as it will only give you side effects and not stop the withdrawal.

Try your best to wait it out and it will stop soon.

Please remember to rate and close this answer thread when you are finished and satisfied.

In the future, for continuity of care, I encourage you to contact me directly at my private web address below. After you ask a direct question, it would be my pleasure to be your dedicated personal physician on this website. My name is Dr. Sheppe, and I am an XXXXXXX doctor working in New York City at NewYork-Presbyterian Hospital, ranked #1 for Psychiatry in the United States ( For a personalized comprehensive evaluation, treatment recommendations, and individual therapy, ask me at HealthCareMagic at this private web address:
Above answer was peer-reviewed by : Dr. Arnab Banerjee

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions
Drug/Medication ,  

Recent questions on  Effexor

doctor1 MD

In the last 3 months I have started taking Effexor XR with my Vyvanse. My Effexor is 37.5 mg once daily and my Vyvanse is 60 mg once daily. Over the last two months I have been experiencing a lot of nausea. However the last three weeks it has gotten worse and there are other things going on. I have been shaky, muscle weakness, fatigue, headaches, general nervous feeling, headaches, chills (not with fever), cloudy mind. Am I having a reaction to the two medications being mixed? What do I need to do to get off the effexor if I am?

doctor1 MD

I am on .5 mg cipralex, I am bloated. I was taking 37.5 mg effexor however tried to raise it to 75 mg very bloated. I am in menopause and have a lot of water retention. Do you think that fetzima might be good for me since it contains no sodium, as effexor not really working anymore at 37.5 mg.

doctor1 MD

My history is taking Lisinipril 10mg, effexor 225, amaryl 1mg, Levothyroxine 100mcg and warfarin.5mg . Am overweight all my life and have type 2 diabetes and underactive thyroid. Recently abt a week ago my Dr put me on Levothyroxine 100mcg bcz tests showed I was too low. Have been off all levothyroxine a week now & blood sugar is being like 84-99. Before it was 99-112. Between Levothyroxine and amaryl----would this change of no levothyroxine and only the amarly plus the other daily meds be causing this change? I feel better mentally and overall better and have more energy. Will appreciate your input. Thanks. Am 74 and generally healthy.

doctor1 MD

Hello, I was on 225mg of Effexor for about a year. I was taking 3 tablets daily, dropped down to 2 tablets daily, then 2 every other day, then 1 every other day. This was gradual over about a month and a half. I lost my health insurance and cannot afford to pay full price. I did not experience feeling off for several days after the last pill. I do not feel depressed, but very light headed off and on with a whooshing sound in my ears. Could these problems start that long after stopping the drug? Or could it be due to something else? If it is from the drug, how long should it last? Thank you very much!

doctor1 MD

I don’t think 375g of Effexor is working, Can I add to it?

doctor1 MD

I've been having dizzy spells but when I get to the hospital they do blood work and EKG. They say it's all normal results. They think it's my anxiety . I'm on effexor xr for depression and GAD. They say I've got health anxiety also. They put me on...

doctor1 MD Still suffering can t with taking Effexor then dont move bowls could even pro long as msny days. If i stop i move bowls that has been backed up a few days but, i...