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Does Duloxetine interact with Oxycodone?

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Posted on Tue, 3 Oct 2017
Question: Is oxycod/acetam 7.5-325mg compatible with duloxetine 30mg cap cit ?
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Answered by Dr. Muhammad Sareer Khalil (28 minutes later)
Brief Answer:
Yes

Detailed Answer:
Hello and welcome

I appreciate your concern

Yes, both are compatible and can be used safely.

Duloxetine does increase oxycodone level slightly via inhibiting it's metabolism in the liver but the interaction is not significant and both can be used together.


wishing you best of health

Thanks
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Muhammad Sareer Khalil

General & Family Physician

Practicing since :2012

Answered : 2919 Questions

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Does Duloxetine interact with Oxycodone?

Brief Answer: Yes Detailed Answer: Hello and welcome I appreciate your concern Yes, both are compatible and can be used safely. Duloxetine does increase oxycodone level slightly via inhibiting it's metabolism in the liver but the interaction is not significant and both can be used together. wishing you best of health Thanks