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Does Amlodipine interact with Benazepril, Simvastatin and Levothyroxine?

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Posted on Mon, 25 Jul 2016
Question: Hi. I am currently taking the following medications and would like to know if there are any contraindications with a natural supplement that I would like to start taking. My medications are as follows: Amlodipine-Benazepril 10-40mg; Simvastatin 20mg; Niacin ER 500mg and Levothyroxine 50mcg. I also take vitamin D drops. The supplement that I am interested in contain the following: CoQ10 100mg; NAC 250mg and PQQ Na2 10mg
Thanks.Is anyone trying to answer my above question?
doctor
Answered by Dr. Panagiotis Zografakis (2 hours later)
Brief Answer:
no interaction anticipated

Detailed Answer:
Hello,

there is no documented interaction between the drugs you've mentioned. PQQ Na2 is not very well documented but the rest (particularly NAC) have been used extensively. No interaction can be anticipated (and no contraindication)...

A general principle regarding drugs and supplements is to avoid using any of them unless it's necessary. Supplements in particular are not usually well documented regarding their benefits (if they have any), side effects, interactions, etc. Personally I don't see the need for using such a supplement but if you'd like to try, then go ahead! There is no documented contraindication for you to do so.

I hope it helps!
Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (34 minutes later)
Thanks for your response. So, what is the difference between interaction, contraindication and side effects?
doctor
Answered by Dr. Panagiotis Zografakis (2 hours later)
Brief Answer:
they are different terms

Detailed Answer:
You're welcome!

Interaction: when two (or more) drugs influence each other's actions.
Contraindication: this is usually a disorder or a medical condition that prevents the patient from using the drug.
Side effect: an untoward effect of the drug.

For example aspirin may interact with other antiplatelet drugs causing more gastrointestinal bleeding than usual.
Aspirin's most well-known side effect is gastrointestinal bleeding.
That's why aspirin is contraindicated in patients with a history of gastrointestinal bleeding or an active peptic ulcer.

I hope this is clear now!

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (2 hours later)
Thanks very much for your responses.
doctor
Answered by Dr. Panagiotis Zografakis (8 hours later)
Brief Answer:
You're welcome

Detailed Answer:
You're welcome!
Glad to help...
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3726 Questions

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Does Amlodipine interact with Benazepril, Simvastatin and Levothyroxine?

Brief Answer: no interaction anticipated Detailed Answer: Hello, there is no documented interaction between the drugs you've mentioned. PQQ Na2 is not very well documented but the rest (particularly NAC) have been used extensively. No interaction can be anticipated (and no contraindication)... A general principle regarding drugs and supplements is to avoid using any of them unless it's necessary. Supplements in particular are not usually well documented regarding their benefits (if they have any), side effects, interactions, etc. Personally I don't see the need for using such a supplement but if you'd like to try, then go ahead! There is no documented contraindication for you to do so. I hope it helps! Kind Regards!