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Does Alendronate interact with antibiotics taken to treat Parkinson's disease?

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Posted on Mon, 25 Jul 2016
Question: I have some new prescriptions, and I want to make sure that they dont conflict with Parkinsonsns disease.
For Parkinsons, I take Carbidopa/Levadopa, 25-100 mg ODT 3 tablets every 3 hours.
PolyethyleneAzilect, 1 mg: 1/day by mouth, for tremors.`
Vesicare, tablet 10 mg, 1 tablet/ in morning, for incontinence.
Oxybutynin, ER 10 mg, 1 tablet at bedtime, for incontinence,
Cyanocobalamin 1000 mcg/ml (B-12) Injection every other week; for B12 deficiency. I also take 1 Vitamin B-12 supplemecnt per day, for Vitamin D deficiency.
Acetaminophen w/Codeine, No. 3; take 1-2 tablets every 4-6 hours for pain.

Esomeprazole Magnesium D-R 40 mg; take 1 tablet per day, by mouth.

Quetiapine Fumarate, 25 mg; take 1 1/2 tablets per day, for hallucinations.

Alendronate Sodium; 70 MG; take 1 tablet every week. Common Brand Name: Fosamax. Alendronate is used to prevent To
and treat certain types of bone loss
(osteoporosis) in adults. Diagnosis on XXXXXXX 27 = Osteoporosis.
To avoid/reduce the risk of injury to your esophagus, follow the instructions very closely. Take this medication by mouth, after getting up for the day and before
taking your first food, beverage or other medication, Take it with a full glass
(6-8 ounces) or 120-240 milliters of plain water. Swallow the tablet whole. Do
not chew or suck on it. This medication MUST be taken on an empty
stomach..... then stay sully upright (preferably 1 to 2 hours). What are the risks &
benefits of long-term use of this medication?
Sincerely, Bremda L. Chase

doctor
Answered by Dr. Olsi Taka (1 hour later)
Brief Answer:
Read below.

Detailed Answer:
I read your question carefully and I understand your concern.

From what I understand the new medication which has been added and worries you is Alendronate? Alendronate is a medication which is used to treat osteoporosis, a condition where bone strength is reduced and there is high risk of fractures (common in women after menopause). In our bones there are cells which create bone matter and cells which destroy it, the balance between their action maintains normal density.
Alendronate acts against cells which destry bone matter, so it is used for osteoporosis as it prevents bone loss. Its benefit is to increase bone density and therefore its strength. Its a benefit which is obtained over months/years of treatment gradually not overnight.

As for its risk I would say it doesn't have many side effects apart from the possibility of gastrointestinal irritation but it is low, most patients tolerate it well (I can speak from personal experience in this case as my mother has taken it for several years). If you have been diagnosed with osteoporosis though, the addition of calcium and vitamin D is also advisable to reach full effect.

Regarding the possible effect on Parkinson’s, or interactions with Parkinson’s medication do not worry, there is no effect on Parkinson’s and no interaction.

I hope to have been of help.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
Dr.
Dr. Olsi Taka

Neurologist

Practicing since :2004

Answered : 3674 Questions

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Does Alendronate interact with antibiotics taken to treat Parkinson's disease?

Brief Answer: Read below. Detailed Answer: I read your question carefully and I understand your concern. From what I understand the new medication which has been added and worries you is Alendronate? Alendronate is a medication which is used to treat osteoporosis, a condition where bone strength is reduced and there is high risk of fractures (common in women after menopause). In our bones there are cells which create bone matter and cells which destroy it, the balance between their action maintains normal density. Alendronate acts against cells which destry bone matter, so it is used for osteoporosis as it prevents bone loss. Its benefit is to increase bone density and therefore its strength. Its a benefit which is obtained over months/years of treatment gradually not overnight. As for its risk I would say it doesn't have many side effects apart from the possibility of gastrointestinal irritation but it is low, most patients tolerate it well (I can speak from personal experience in this case as my mother has taken it for several years). If you have been diagnosed with osteoporosis though, the addition of calcium and vitamin D is also advisable to reach full effect. Regarding the possible effect on Parkinson’s, or interactions with Parkinson’s medication do not worry, there is no effect on Parkinson’s and no interaction. I hope to have been of help.