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Does Adderral Use Increase GGT And ALT Levels?

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Posted on Wed, 29 Apr 2015
Question: Does aderral use increase GGT and ALT? Two years ago, ALT and AST were both 20 after 12 days of no alcohol, but daily adderall use. Last round AST/28 and ALT 49 and GGT 74 after 12 days of no alcohol and daily adderall use. Bilirubin went from .6 to .8.
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Answered by Dr. Chalapathi Rao Achanta (16 minutes later)
Brief Answer:
Yes

Detailed Answer:
Good morning
I am sorry to hear about your ill health
Aderral is known to cause elevation in liver enzymes due to amphetamine related liver toxicity. But after discontinuatiom of aderral, the illness is self limited and usually and resolves with conservative and expectant management
If I was your doctor I also like to perform blood tests to rule out hepatitis c and b infections which could also explain this Elevated enzymes

Hope this would answer your question

Wish you a speedy recovery
Above answer was peer-reviewed by : Dr. Raju A.T
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Follow up: Dr. Chalapathi Rao Achanta (28 minutes later)
I have been tested for Hep A,B and C, all negative and an "untemarkable" livet ultrasound 2 years ago. The GGT is disturbing. Can this indicate fibrosis? I had been ilimonating liver disease dueto the AST and ALT ratio.
doctor
Answered by Dr. Chalapathi Rao Achanta (18 hours later)
Brief Answer:
GGT elevation doesnt always indicate liver fibrosis

Detailed Answer:
Good morning
GGT elevation may be because of a recent alcohol consumption and need not always indicate liver fibrosis. The normal ultrasound two years ago is reassuring.
To detect and categorize liver fibrosis, I would recommend an ultrasound liver elastography (different from the standard abdominal ultrasound) which is now a routine practice.
To check the trend in the liver functions, I would recommed a repeat check of your liver enzymes after 4 weeks after complete abstinence from all drugs, medicines, alcohol and energy supplements.
Hope this answer will you solve your problem
Wish you a speedy recovery
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Chalapathi Rao Achanta

Gastroenterologist

Practicing since :2004

Answered : 49 Questions

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Does Adderral Use Increase GGT And ALT Levels?

Brief Answer: Yes Detailed Answer: Good morning I am sorry to hear about your ill health Aderral is known to cause elevation in liver enzymes due to amphetamine related liver toxicity. But after discontinuatiom of aderral, the illness is self limited and usually and resolves with conservative and expectant management If I was your doctor I also like to perform blood tests to rule out hepatitis c and b infections which could also explain this Elevated enzymes Hope this would answer your question Wish you a speedy recovery