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Diabetic Patient. Did Elisa Test Few Months After Exposure. Chances Of HIV Infection?

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Posted on Tue, 5 Mar 2013
Question: i am diabetic patient. did elisa test after 4 months of exposure. test results shows 0.007 negative over a cut off of 0.4 . can you please explain the possibility of hiv infection?
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Answered by Dr. CS Narayan (33 minutes later)
Hello and thanks for your query.

I shall make an effort to provide you with good professional recommendations specific to your questions.

The ELISA test done after 4 weeks of exposure is taken as valid, so in your case the test apparently as NEGATIVE - as the level of antibodies in your serum is way below the cut off number of 0.4 - so the possibility of you having an HIV infection looks very bleak.

The possibility of having HIV full blown infection or not with your situation only with a ELISA test report - has to consider the following,

1. Diagnostic tests have limitations and have to be synced with clinical status.
2. ELISA is a high sensitivity test - that means it shows up as positive in a large number of patients who are really positive.

And to confirm HIV infection, a second test called Western Blot test is performed if ELISA is initially positive. To sum up, a clinical case of HIV will need a combination of ELISA and Western Blot tests to confirm initially.

Let me know if I have missed out any other concern in your question.

Yet again, I duly appreciate your query to me, I do hope that you have found something useful to help you and I shall be glad to answer any further apprehensions.

Sincerely,

Dr Sujeet N Charugulla,
MBBS, MD.
Consultant Physician.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. CS Narayan

General & Family Physician

Practicing since :2004

Answered : 546 Questions

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Diabetic Patient. Did Elisa Test Few Months After Exposure. Chances Of HIV Infection?

Hello and thanks for your query.

I shall make an effort to provide you with good professional recommendations specific to your questions.

The ELISA test done after 4 weeks of exposure is taken as valid, so in your case the test apparently as NEGATIVE - as the level of antibodies in your serum is way below the cut off number of 0.4 - so the possibility of you having an HIV infection looks very bleak.

The possibility of having HIV full blown infection or not with your situation only with a ELISA test report - has to consider the following,

1. Diagnostic tests have limitations and have to be synced with clinical status.
2. ELISA is a high sensitivity test - that means it shows up as positive in a large number of patients who are really positive.

And to confirm HIV infection, a second test called Western Blot test is performed if ELISA is initially positive. To sum up, a clinical case of HIV will need a combination of ELISA and Western Blot tests to confirm initially.

Let me know if I have missed out any other concern in your question.

Yet again, I duly appreciate your query to me, I do hope that you have found something useful to help you and I shall be glad to answer any further apprehensions.

Sincerely,

Dr Sujeet N Charugulla,
MBBS, MD.
Consultant Physician.