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Dr. Andrew Rynne
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Dr. Andrew Rynne

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Detected with lymphoma. What treatment should be done?

Answered by
Dr.
Dr. Indranil Ghosh

Oncologist

Practicing since :2004

Answered : 1506 Questions

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Posted on Thu, 4 Apr 2013 in Cancer
Question: I am enclosing the reports of my father who has been detected with LYPHOMA.

I need to know how critical it is and what is the best treatment for the same. Further , if we can get the contacts of the best Oncologist in Dehi&ncr who could be refered for the same.
===============================
* This is a computer generated report no signatured required.
* Content of this report is only an opinion not the diagnosis.
* Report shall not be reproduced except in full without written approval of the laboratory.
Dr XXXXXXX Malhotra
XXXXXXX Consultant & HOD
This Test Is Perofrm At Outsource
1 of 3
TEST REPORT STATUS FINAL
MRD NO 0000
ENCOUNTER
NO
Name XXXXXXX
Ward/Bed No.
Sex/Age Male/73 Yrs.
Referred By Dr. V.P Bhalla\Dr XXXXXXX Goel\Dr Ravinder Vats(GIST)
Lab Ref No 0000
Sample Date 13/03/2013 14:20
Report Date 14/03/2013 16:44
Reporting Stage Final

Receiving Date 13/03/2013 14:21

/
Histopathology and Cytopathology
Test Name:-IHC ( Immunohistochemistry 3 marker) *
Referring Clinician:- Dr. V. P. Bhalla/Dr. XXXXXXX Goel/Dr. Ravinder Vats
Histopathology Number: - S-815/13
Gross Description:-
Specimen received in container labeled as XXXXXXX.
Received single soft tissue mass measuring 4x3x2 cm. outer surface is
lobulated. Cut section is grey white. Representative sections submitted in
cassettes A-F:
A-B: One lymph node
C-D: One lymph node
E-F: lymph node
Microscopic Description:-
Sections show enlarged lymph node with complete effacement of architecture
and replacement by sheets of monomorphic cells. These cells show enfolded
nuclear membrane. Nuclear chromatin is moderately dense. Few mitotic cells
are seen. Extension of cellular infiltrate into perinodal fat is present.
Immunohistochemistry:
Cells show diffuse positivity with CD 20 and CD 10. Few CD 3 positive
reactive T cells seen. Cyclin D1 is negative. Proliferative index is about
35% in focal areas.
Comment:
Histological features are those of non Hodgkin's B cell lymphoma. Suggestive
of a diffuse large B cell lymphoma evolving from follicular lymphoma.
Final Diagnosis:- Right axillary lymph node, biopsy:
- Non Hodgkin's B cell lymphoma suggestive of a diffuse large B cell
lymphoma evolving from follicular lymphoma.
* This is a computer generated report no signatured required.
* Content of this report is only an opinion not the diagnosis.
* Report shall not be reproduced except in full without written approval of the laboratory.
Dr XXXXXXX Malhotra
XXXXXXX Consultant & HOD
This Test Is Perofrm At Outsource
2 of 3
TEST REPORT STATUS FINAL
MRD NO 0000
ENCOUNTER
NO
Name XXXXXXX
Ward/Bed No.
Sex/Age Male/73 Yrs.
Referred By Dr. V.P Bhalla\Dr XXXXXXX Goel\Dr Ravinder Vats(GIST)
Lab Ref No 0000
Sample Date 13/03/2013 14:20
Report Date 14/03/2013 16:44
Reporting Stage Final
:
Receiving Date 13/03/2013 14:21
/
--------------End of Report--------------
* This is a computer generated report no signatured required.
* Content of this report is only an opinion not the diagnosis.
* Report shall not be reproduced except in full without written approval of the laboratory.
Dr XXXXXXX Malhotra
XXXXXXX Consultant & HOD
This Test Is Perofrm At Outsource
3 of 3
TEST REPORT STATUS FINAL
MRD NO 0000
ENCOUNTER
NO
Name XXXXXXX
Ward/Bed No.
Sex/Age Male/73 Yrs.
Referred By Dr. V.P Bhalla\Dr XXXXXXX Goel\Dr Ravinder Vats(GIST)
Lab Ref No 0000
Sample Date 13/03/2013 14:20
Report Date 14/03/2013 16:44
Reporting Stage Final
:
Receiving Date 13/03/2013 14:21
/
doctor
Answered by Dr. Indranil Ghosh 2 days later
Dear XXXXXXX
Thanks for writing in.

It appears that your dad has got a high-grade lymphoma on the background of a pre-existing low-grade lymphoma. Probably the low grade lymphoma was undetected earlier.

Though this type of lymphoma is potentially curable, with his age and other problems like diabetes, it will be difficult to deliver proper doses of chemotherapy. This could compromise the outcome. Treatment is quite intensive and can cause serious problems like infections.

In delhi/NCR there are various options available. Few options are AIIMS, Fortis Noida (Dr XXXXXXX Singhal), Batra Hospital (Dr K Medhi), XXXXXXX XXXXXXX Cancer Hospital (Dr DC Doval) and many more.

Hope I have answered your query. I will be available to answer any followup queries.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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