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Delayed periods, abdominal pain. On meprate medication. Pregnancy test negative. History of PCOS. Pregnancy?

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Internal Medicine Specialist
Practicing since : 1998
Answered : 1579 Questions
My wife (aged 31) is with PCOS and under medication for past one year. Usually she will get cycle (period) between 35 to 39 days. Now she is running 50th day. For the past 6 months she is taking GMET 500 mg (2 per day) and for past 50 days she is taking EVE CARE SYRUP (3 times per day) and OVACARE FORTE (for past 45 days). Did home pregnancy test on 42nd day and found negative. Met Doctor and she told to take MEPRATE (2 per day) for 5 days. She has taken MEPRATE (2 per day) for 5 days from her 43rd to 47th Day. Now she is running 51st Day. 4 days over after stopping MEPRATE. Now, No symptom of getting period. Only little abdomen pain. Whether SHE IS CONCEIVED now? WHEN WE SHOULD REPEAT THE TEST? Whether any chance for getting pregnant this time? What are your suggestions and Advices? How long should we wait to repeat the test?
Posted Thu, 19 Apr 2012 in Early Pregnancy Signs and Symptoms
Answered by Dr. Jasvinder Singh 1 hour later
Thanks for posting your query.

Ovacare is a nutritional supplement. It is a preparation given to women who are trying to conceive. Meprate is a synthetic progestogen structurally related to natural progesterone and used in the treatment of secondary amenorrhoea and for abnormal uterine bleeding not due to organic pathology,

From your wife’s symptoms, the secondary amenorrhea seems to be due to PCOS and not pregnancy. However to completely rule out pregnancy, your wife can get a serum HCG test done which is more specific than a urine test or a do a urine pregnancy test using a kit commonly available at the chemist.

You can do these tests at any time as hCG can be detected in urine even after a week after the date of the missed period.

In case these tests come negative, then apart from Gmet for PCOS, other treatment options should be considered. Other options include hormones like Injectable HCG, Hmg, FSH, GnRH and assisted reproduction techniques like IUI, IVF, GIFT AND ICSI may also be used. It can also be treated surgically and this procedure is known as drilling. Other modes of treatment are laparoscopic surgery, laparotomy or surgery for complicated ovarian cysts. Please consult a gynaecologist who would be able to completely evaluate your wife and prescribe appropriate therapy.
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Wishing you good health.

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