Frankly speaking there is no painkiller which is absolutely safe, also painkillers only give an analgesic
effect. If there is swelling in the joint then the joint damage will continue to increase.
Also once joints start getting damaged and deformities appear then there is no way of reversing deformity
Out of the pain medication paracetamol and tramadol combination drugs are the safest. The rest of the medicines have a similar side effect profile.
Hope I have answered your question. Let me know if you need any other information.