Question: Back in 1975 how good was blood sugar control of an insulin dependent lady. My mom had acquired type 1 diabetes mellitus. I heard that the high blood sugar environment of the uterus could harm the virilization of the foetus. Let me be clear; the testicles and penis form during 12 weeks into the pregnancy. I can only think the high blood sugar levels would decrease the testosterone level in the uterus and harm the masculinisation of the baby. I know later on the feats makes his own insulin but not at 12 weeks. Is there some trusty to what I think?

she did not have gestational diabetes. She was taking insulin even before she got pregnant. When I was 5 my brother told me I had a small penis.
Is it possibly linked to my mom being diabetic before and during pregnancy. Also I am a couple inches shorter than my brother.

What is expected bio available testosterone level in a healthy male 38 years old; normal weight; physically active; non smoking.
I ask the same question about SHBG; Prolactin
also ; a question; what do you know about how kidney disorder effect childhood growth. If a child did not use public restrooms as a kid out of fear would this effect their calcitriol level and parhyroid hormone level to cause reduced height? Bascially from 5 to 12 years old I did not urinate at school daily from 7am to 3pm. Please comment.

What is HB; what is erythropoietin. Also you said renal problem can effect height due to physical illness? I was not sick as a child. But for 7 years i did not go to the bathroom during the daytime. Well, at least for 5 of those years. I urinate when I woke up; then go to school and would withhold XXXXXXX to urinate until I got home. I always urinated before going to bed. Could the daytime not urinating cause chronic renal insufficiency or an effect on the bone growth and metabolism? The question is that if you do not urinate for 8 hours per day ; during school day; will this cause a renal insufficiency that would effect the calcitriol level and parathyroide hormone? Would this reduce height growth?

Dear Dr.

A question; may I ask?
Are you taller than your dad? If so; are your hands larger than your dad's; do you know? I believe that height is related to calcium AND protein intake because long bones require protein to make the muscle that relates to them. Hands and foot growth are less protein dependent but more indicative of growth hormone and calcium metabolism. Now if I may say; i do not find it normal that i have smaller hands than my dad unless i had a calcium metabolism deficiency.
I am inclined to think that without the deficiency i would have been quite a bit taller.
For example my hand length is only 19cm; compared to my dad which is 19.5cm. Also his feet are size 9.5; mine are 9. My brother are size 10 and he is 5 9.

Concerning your point about kidney disease; yes i understand what you are saying. But studies have shown that even when a bladder is 60% full renal function is decreased (lower GFR). Of course, if I had to urinate because it was full to the point of you can no longer hold it ; i would urinate. Also even mild chronic renal insufficiency is known to cause growth retardation. And without other symptoms typical of kidney disease. It seems that growth retardation can be the first sign and asymptomatic of normal kidney disease. As in stage 1 or 2 kidney disease. PLEASE COMMENT

So you know my parents had considered putting me on growth hormone but the doctor advised against it because he felt i would not be shorter than 95% of other men. PLEASE COMMENT

i do wish however he had done some simple tests to see if there was any other reason why I was growing slowly.
PLEASE COMMENT

You are the same height as your dad?
Can I ask please how tall was your mom?
You know you are taller than the average XXXXXXX This is not the case for me as I live in the West. Imagine if you were 5 foot 2; then you would understand a bit how I feel. Average 20 year old Americans are 5 10.5. I am five 7. So I have a bit of a handicap in sport and in dating. Many USA women will not date guys shorter than 5 10. 5 9 is even short. I know in XXXXXXX it is very different and height is not so important. This is obvious otherwise my parents would have done more than take me once to a general doctor to see if I should get growth hormone. When he said no; that was it. No extra tests; nothing done to see why I was short.

I have looked into surgical height methods; which ones are the best? Least painful with least side effects. I am no coward to surgery as I already broke both my femurs during a paragliding accident 10 years ago.
Please comment.

I think I was average height age 3 to 6 or so. But my parents never kept any growth charts so I would not know. When I went to school aged 5 or so ; I stopped urinating normally during the day at school. This started because once at a public bathroom my brother told me I had a small penis.

They use GFR to show kidney function. Studies have shown that with an even minor reduction in GFR growth can be harmed. And studies have shown that a full bladder (even 60% reduces growth).
Would it be of use to test my calcitriol or parathyroide hormone. If harm had been done it is likely that you would see altered levels perhaps even now? And for the ecographie of kidneys what to look for? Dialated urethers?

Interesting to know I gained weight becoming chubby starting around age 9; this would correspond to a reduced kidney function? I kind of feel that if you don't urinate for 8 hours each day you are reducing your metabolism. And clearly the bone metabolism as kidney effect this. It is like I stopped growing up so I became chubby. It is around 10 when they noticed I Was short. They were concerned. Soon i went to a different school with toilets i could use more regularly. By age 12 I tall enough that I was not in the bottom 5% so they were less concerned.

I had my sperm count checked in 2012 and it was below average at 50 million/ML. Total was around 180 million.
My bio available testosterone was around 2.24 nmol/L. Should it not be something like 4 or so? My total Testosterone was around 15 or 440 (using US units). Even this should be quite a bit higher. My SHBG was around 50. My prolactin was 17 once; and 20 more recently. All these point to an androgen deficiency which i have probably had my whole life. And certainly during puberty. My mom had Type I diabetes; which she acquired while living in India; a virus attached her pancreas. She was already taking insulin ; one year before I Was born in 1975. Does this have an effect on fetal gonad development (as in testicles and penis); and would this cause me to perhaps grow to be less tall?

Would growth hormone have any impact on my hands or feet or size of larynx ; as these have less growth plates then femurs? What if I supplemented this with androgenic testosterone and HCG (perhaps 2000IU 3 times a week)? And an aromatese inhibitor such as arimadex. I think my voice also suffered some and is not deep as it should be. Do you have an idea of the type of testosterone that I would take; the androgenic one (not anabolic). I just was never exposed to as much testosterone as I should have been. I read stories about guys even 26 who took testosterone and it helped them a lot.

Please comment.