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Can Xarelto and Instaflex be taken together?

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Posted on Mon, 14 Jul 2014
Question: I am a 81 years old and now using xarelto and wondering if I can use instaflex? There is white willow bark extract , 15 percent salicin, in ingredient list of instaflex. Can I safely take it with xarelto?? Bone to bone knees with arthritis. XXXXXX florida

Instaflex joint support
Glucosamine sulfate 1500 mg
Methylsulfonylmethane 500 mg
White willow bark 250 mg
Ginger root extract 250 mg
Boswellia serrata extract 125 mg
Turmeric root extract 50 mg
Cayenne fruit 50 mg
Hyaluronic acid 4mg
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Answered by Dr. Shoaib Khan (8 hours later)
Brief Answer:
Rare drug interaction +; otherwise safe

Detailed Answer:
Hello sir and welcome.

Thank you for writing to us.

I have gone through your query with diligence and would like you to know that I am here to help.

Although there have been various concerns raised about some variants of instaflex ibteracting with xarelto, the joint support variant of instaflex is found to be safe to use with xarelto.

I would also like to point out that the willow bark in the joint support instaflex has an aspirin-like effect when taken with xarelto which causes the blood to thin, imposing an increased risk to micro-hemorrhage. So if at all you experience gum bleeding or rectal bleeding I would request you to report to your doctor at the earliest. Other than this, which is also rarely seen, there are no other side effects or interactions you need to worry about.

I hope you find my response both helpful and informative. Please feel free to write back to me for any further clarifications, I would be more than happy to help you.

Best wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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Can Xarelto and Instaflex be taken together?

Brief Answer: Rare drug interaction +; otherwise safe Detailed Answer: Hello sir and welcome. Thank you for writing to us. I have gone through your query with diligence and would like you to know that I am here to help. Although there have been various concerns raised about some variants of instaflex ibteracting with xarelto, the joint support variant of instaflex is found to be safe to use with xarelto. I would also like to point out that the willow bark in the joint support instaflex has an aspirin-like effect when taken with xarelto which causes the blood to thin, imposing an increased risk to micro-hemorrhage. So if at all you experience gum bleeding or rectal bleeding I would request you to report to your doctor at the earliest. Other than this, which is also rarely seen, there are no other side effects or interactions you need to worry about. I hope you find my response both helpful and informative. Please feel free to write back to me for any further clarifications, I would be more than happy to help you. Best wishes.