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Can Methotrexate Withdrawal Cause Diverticulitis,sacroilitis And Body Aches?

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Posted on Mon, 17 Feb 2014
Question: I am currently experiencing diverticulitis, sacroilitis and many aches and pains that I haven't had before. I was on methotrexate for years and stopped about a year ago. I started it back up about two weeks ago. Could all of these symptoms be related?
doctor
Answered by Dr. Dr. Shruti Rijhwani (3 hours later)
Brief Answer: Follows. Detailed Answer: Dear Madam, Thank you for posting your query on XXXXXXX Well looking into your query I will like to tell you that you could be having an entity that is known as seronegative spondyloarthropathy for which probably you were started on Methotrxate . Your uveitis , sacroillitis and diverticulosis can be all part of its spectrum . But it has got different categories , which one you fit in requires a thorough evaluation . You treating doctor was right in satarting methotrexate for this but it should not have been stopped which might have resulted in flare of disease. Since you have started it again it will come under control but it is going to take some timefor that . Take care. Dr. Shruti
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Dr. Shruti Rijhwani (5 minutes later)
I was diagnosed with iritis about 15 years ago and put on methotrexate . I think they said it feel under AS. I have not had the problem in so many years that I quit. Should I actually start back?
doctor
Answered by Dr. Dr. Shruti Rijhwani (11 minutes later)
Brief Answer: Follows. Detailed Answer: Dear Madam, AS stands for ankylosing spondylitis which comes under seronegative spondyloarthropathy . To start or not to start decision will be taken by your treating doctor after seeing all the reports and examining you . But since you are having aches and pains that is an indication that you need the medicine . Dr. Shruti
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Shruti Rijhwani (17 minutes later)
Thank you.
doctor
Answered by Dr. Dr. Shruti Rijhwani (47 minutes later)
Brief Answer: Follows. Detailed Answer: Dear Madam, Its my pleasure if I would have been of any help to you. Dr. Shruti
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Shruti Rijhwani

Rheumatologist

Practicing since :2008

Answered : 2366 Questions

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Can Methotrexate Withdrawal Cause Diverticulitis,sacroilitis And Body Aches?

Brief Answer: Follows. Detailed Answer: Dear Madam, Thank you for posting your query on XXXXXXX Well looking into your query I will like to tell you that you could be having an entity that is known as seronegative spondyloarthropathy for which probably you were started on Methotrxate . Your uveitis , sacroillitis and diverticulosis can be all part of its spectrum . But it has got different categories , which one you fit in requires a thorough evaluation . You treating doctor was right in satarting methotrexate for this but it should not have been stopped which might have resulted in flare of disease. Since you have started it again it will come under control but it is going to take some timefor that . Take care. Dr. Shruti