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Can Lubiprostone Be Used In An Advanced ALS Patient With Breathing Issues Because Of Diaphragmatic Involvement?

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Posted on Fri, 22 Jan 2021
Question: My ALS patients have a chronic dysbiosis with an overgrowth of yeast (Candida) and invasion into their intestinal wall(s) and blood, stool and urine tests that indicate they have mounted an immune response with elevated antibodies and often have tests such as labcorp's expanded bowel panel that are positive for severe Crohn's. They do not respond well to the common antifungals even though I rotate them and use them at high doses. They lose weight and have evidence of chronic subclinical endotoxemia with endotoxins in their blood. There is a drug lubiprostone that did show effectiveness in improving the intestinal permeability. Do you think this can be used in an advanced ALS patient who is having trouble breathing because of diaphragmatic involvement?
Any other thought on other more safe remedies to stop the endotoxin poisoning, etc.
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Answered by Dr. Dr. Jolanda (3 hours later)
Brief Answer:
use it

Detailed Answer:

Hello and welcome,

I can understand your concern

As you explain the history the situation is serious.
In my knowledge Lubiprostone doesn't have diect side effects in the breathing process. Its side effects are mainly related to gastrointestinal system.

I would recommend you to use this medication given such severe condition and to monitor closely the situation. As you explain you have already used the standart treatment and nothing improvement.
I hope to have been helpful

Regards and feel free to ask me again

Dr.Jolanda
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.
Above answer was peer-reviewed by : Dr. Kampana
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Dr. Dr. Jolanda

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Can Lubiprostone Be Used In An Advanced ALS Patient With Breathing Issues Because Of Diaphragmatic Involvement?

Brief Answer: use it Detailed Answer: Hello and welcome, I can understand your concern As you explain the history the situation is serious. In my knowledge Lubiprostone doesn't have diect side effects in the breathing process. Its side effects are mainly related to gastrointestinal system. I would recommend you to use this medication given such severe condition and to monitor closely the situation. As you explain you have already used the standart treatment and nothing improvement. I hope to have been helpful Regards and feel free to ask me again Dr.Jolanda