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Can Carvedilol Cause Lupus?

Posted on Wed, 9 Aug 2017

Question: Good Morning Dr. Shoman,
I am continuing to try the new channel blocker, still experiencing the shaky feeling etc. will see my Primary Dr. in August. I will, at that time, give her your recommendations and shall see what happens. In addition, my Primary Dr. thinks I may have drug induced Lupus from the Carvidirol, not sure what that means - perhaps you could explain. thank you

Answered by Dr. salah saad shoman (57 minutes later)

Brief Answer:
Rarely occur from carvidirol

Detailed Answer:
Dear Ms, I have gone through your question and I understand your concerns . Drug induced lupus rarely occurs from carvidirol. However , it was reported to occur in several cases .. drug induced lupus is an autoimmune disorder that affects multiple body organs and usually occur after 3-6 months from using the medication, Symptoms may include:
Blurred vision
Fever
General ill feeling (malaise)
Joint pain
Joint swelling
Loss of appetite
Pleuritic chest pain
Skin rash that gets worse with sunlight. (It may appear as a "butterfly" rash across bridge of nose and cheeks.)
This should be diagnosed by an antihistone antibody and an lupus antibody test to confirm the diagnosis . Usually symptoms resolve few days to few weeks after stopping the medication, but an anti-inflammatory as non steroidal anti-inflammatory or corticosteroids may also be needed . I hope I answered your question.

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. salah saad shoman (2 days later)

Thank you for your prompt reply. I seem to be receiving differing opinions from different Doctors. My Rheumatologist if positive I have Lupus, my Hematologist is not sure what I have and my Primary Dr. thinks I have drug induced Lupus. My question after giving you that background, is, do "pruney" finger tips, tingling in hands also point to Lupus? I did have a rash on my neck and chest which went away after receiving a cortisone shot, however my face remains very red, not a rash - just very red, like a sunburn - any ideas? XXXXXXX XXXX p.s. I'm trying to get a cohesive or definitive answer and there may not be one!

Answered by Dr. salah saad shoman (18 hours later)

Brief Answer:
Take the tests to confirm

Detailed Answer:
Dear Ms, blue or purple discoloration of the fingers is described as Raynaud's phenomenal which occurs in drug induced lupus or lupus .. I would recommend you take the antihistone and the antiluous antibody tests , if found positive then stop the medication and follow up on the tests and symptoms .. if the tests returned to normal and the symptoms disappeared then this confirms the drug induced lupus.. if not then this indicates lupus and you should start managing accordingly. I hope you find this helpful

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. salah saad shoman (2 hours later)

Dr. Shoman,
Thank you for your response. My finger tips are not purple or blue but instead a light pink and very dry looking. Don't know if this makes a difference in the prognosis but thought I should mention it. XXXXXXX XXXX p.s. will take all the info you provided to my Primary Dr. next visit. Thank you again.

Answered by Dr. salah saad shoman (18 hours later)

Brief Answer:
Could be related to lupus

Detailed Answer:
Dear Ms, lupus or drug induced lupus may present with skin affection similar to psoriasis which involves very dry and may be peeling pink finger tips .. I hope you find this helpful

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. salah saad shoman (4 hours later)

Thank you so much for your clear and concise answers. You have been most helpful. XXXXXXX XXXX

Answered by Dr. salah saad shoman (18 hours later)

Brief Answer:
It has been a pleasure helping you

Detailed Answer:
you are welcome, kind regards

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Above answer was peer-reviewed by : Dr. Kampana