Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

184 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Can Amitriptyline help cure esophageal hypersensitivity?

Answered by
Dr.
Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16155 Questions

default
Posted on Fri, 6 Nov 2015 in General Health
Question: Can amitriptyline be prescribed for sensitive oesophagus? Will it cure the dry throat & "lump" in the back of my throat?
doctor
Answered by Dr. Michelle Gibson James 29 minutes later
Brief Answer:
not normally used for this

Detailed Answer:
HI, thanks for using healthcare magic

Amitriptyline was originally intended as an anti depressant but it is not mainly used to treat nerve related pain.

It is not normally used to treat dryness of the throat or feeling of a lump at the back of the throat.

This would normally be treated with oral anti histamines and topical nasal sprays because most commonly due to post nasal drip. Some persons are not aware of the drip, this is the case in 20% of persons.

Eg of sprays are flonase, rhinocort, nasonex , nasocort

It can take 1 to 3 weeks, in some cases, of consistent use , for a response

I hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Michelle Gibson James 22 hours later
Thank you. I've had symptoms of GERD for nearly 2 years, but a gastroscopy shows all clear except for a very small Hiatus Hernia. Dryness of throat and feeling of a lump there also appear to be symptoms of reflux, so post nasal drip has never been considered. (I also burp a lot). As acid blockers & other acid reducing medicines don't have any effect, I'm told that I have a sensitive oesophagus and that further treatment i.e. surgery etc. would therefore be ineffective. 10mg Amitriptyline once daily has been prescribed to deaden the nerves, but this seems a powerful drug for this purpose & I'm very reluctant to take it. I've never been depressed and am otherwise very fit & healthy & take no other medications. Your comments would be greatly appreciated. With regards, XXXXXXX XXXXXXX
doctor
Answered by Dr. Michelle Gibson James 8 minutes later
Brief Answer:
not at levels normally use for depression

Detailed Answer:
HI

If you wish, since you have a history of reflux, you can combine the reflux treatment with treatment for post nasal drip to see if this has an effect.

Some persons have both conditions existing at the same time. If there is going to be an effect, it should be within 1 to 3 weeks.

If after this interval there is no improvement , can consider alternative. If you are not comfortable with this then you can use the amitriptyline, the dose is small, not at the levels used to treat depression but at the levels used to treat nerve related pain/discomfort.

Should use at night, since it causes drowsiness

Please feel free to ask anything else
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions
Drug/Medication ,   ,   ,  
Medical Topics ,  

Recent questions on  Anti depressant

doctor1 MD

I have had arthritis for thirty years, I am just starting to grunt and groan at the smallest irritation over any annoyance and walking, 73 years, I have tried green tea to calm my self down, I cant get into a calm peaceful state of mind, I used to...

doctor1 MD

I have been having dry mouth after having some infection of the teeth. Had two bad ones extracted. My ENT special9st has prescribed steroid for me. I take lot of medicines including Zolof. How is the interaction? I was reading on WebMD that...

doctor1 MD

Yes I was prescribed zyprexa years ago for depression when going through a divorce. I've tried to stop it twice and this is my third and final time. I've been tapering off it for over a year now since the last two attempts failed miserably. Now...

doctor1 MD

Hi, I suffer from pain in the lower and middle part of my stomach . It becomes a lot more pronounced when I opsuh down on my stomach. Pain regularly radiates into my pelvic region. I have been diagnosed IBS and was on antidepressants to control the spasms. But this pain just never stops. Is there somethinh I can say to my doctor to assist him in diagnosing me? Thank you,

doctor1 MD

Hi . I am on antidepressants for about 7 years now. I was so slim but suddenly gained a lot of weight. I began to have an enlarged liver of 17.5 measure. And then the latest X-ray showed that i began to have a bulky spleen . Blood tests are Ok except for Gout which is high. So does this condition mean anything? or could i have a hidden cancer in some part of my body especially that my belly is so fat. I am 35 years old

doctor1 MD

I am sometime getting anxious over small issues and myhealth gets spoiled