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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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As per attachment., please help

Answered by
Dr.
Dr. Bhagyesh V. Patel

General Surgeon

Practicing since :1999

Answered : 14761 Questions

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Posted on Fri, 5 Apr 2019 in Lump
Question: As per attachment., please help
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Follow up: Dr. Bhagyesh V. Patel 0 minute later
As per attachment., please help
doctor
Answered by Dr. Bhagyesh V. Patel 17 hours later
Brief Answer:
Isolated hemorrhoids do not give rise to Calprotectin.

Detailed Answer:
Hello and welcome to Ask A Doctor services.
I have read query for your mother with attachment details.

* The Calprotectin is a member of S 100 family of polypeptide protein.
* The Calprotectin gets elevated in number of inflammatory bowel conditions, mainly
inflammatory bowel diseases.

* There are not enough evidences where mere presence of hemorrhoids without
inflammation of the bowel give rise to this protein level in the stool assay.

However, kindly provide further symptomatic details so that I can answer your query more precisely.

1. Current symptoms in details.
2. Bowel movements details.
3. Any alteration in weight or other systemic parameters ?

Awaiting for your response.
Regards.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
doctor
Answered by Dr. Bhagyesh V. Patel 0 minute later
Brief Answer:
Isolated hemorrhoids do not give rise to Calprotectin.

Detailed Answer:
Hello and welcome to Ask A Doctor services.
I have read query for your mother with attachment details.

* The Calprotectin is a member of S 100 family of polypeptide protein.
* The Calprotectin gets elevated in number of inflammatory bowel conditions, mainly
inflammatory bowel diseases.

* There are not enough evidences where mere presence of hemorrhoids without
inflammation of the bowel give rise to this protein level in the stool assay.

However, kindly provide further symptomatic details so that I can answer your query more precisely.

1. Current symptoms in details.
2. Bowel movements details.
3. Any alteration in weight or other systemic parameters ?

Awaiting for your response.
Regards.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Bhagyesh V. Patel 10 hours later
1. No symptoms currently only the up and down faecal calprotectin level 2. I don't know what this mean 3. I think no
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Follow up: Dr. Bhagyesh V. Patel 0 minute later
1. No symptoms currently only the up and down faecal calprotectin level 2. I don't know what this mean 3. I think no
doctor
Answered by Dr. Bhagyesh V. Patel 3 hours later
Brief Answer:
follow up .

Detailed Answer:
Hello and thanks for the details.

* As there is associated Sjogren syndrome, immunology plays a very vital role in this
case for alternating levels of certain inflammatory markers including Calprotectin.

* Till the drugs are mentioned, she is on best molecules for her condition ; so in my
opinion

- should not be stressed out much with alterations in Calprotectin levels ( which is a
supportive measure only, not of dangerous critical situation )
- you should watch for any problematic symptom in between as constipation or diarrhea
with or without blood
- maintain chart of her body weight on regular basis
- continue regular medications
- be in regular follow up with the consultant

- discuss the possible benefits of anti oxidants in her case with the treating consultant
during next visit
- dietary controls to avoid spices, non veg till possible
- she must meditate herself with YOGA which will help tremendously at micro molecular
levels on long term measures

Wish her best health.
Regards.

Dr Bhagyesh
Above answer was peer-reviewed by : Dr. Prasad
doctor
doctor
Answered by Dr. Bhagyesh V. Patel 0 minute later
Brief Answer:
follow up .

Detailed Answer:
Hello and thanks for the details.

* As there is associated Sjogren syndrome, immunology plays a very vital role in this
case for alternating levels of certain inflammatory markers including Calprotectin.

* Till the drugs are mentioned, she is on best molecules for her condition ; so in my
opinion

- should not be stressed out much with alterations in Calprotectin levels ( which is a
supportive measure only, not of dangerous critical situation )
- you should watch for any problematic symptom in between as constipation or diarrhea
with or without blood
- maintain chart of her body weight on regular basis
- continue regular medications
- be in regular follow up with the consultant

- discuss the possible benefits of anti oxidants in her case with the treating consultant
during next visit
- dietary controls to avoid spices, non veg till possible
- she must meditate herself with YOGA which will help tremendously at micro molecular
levels on long term measures

Wish her best health.
Regards.

Dr Bhagyesh
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Bhagyesh V. Patel 6 hours later
My mother on november 2018 already did endoscopy and colonoscopy... And there were two non malignant polip (only inflamation polip and already taken out), currently under medication myfortic 180mg once daily, budenofalk once daily and salofalk once daily,.. But why the calprotectin faecal level still fluctuated so sharply?
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Follow up: Dr. Bhagyesh V. Patel 0 minute later
My mother on november 2018 already did endoscopy and colonoscopy... And there were two non malignant polip (only inflamation polip and already taken out), currently under medication myfortic 180mg once daily, budenofalk once daily and salofalk once daily,.. But why the calprotectin faecal level still fluctuated so sharply?
doctor
Answered by Dr. Bhagyesh V. Patel 2 hours later
Brief Answer:
immune mechanics beyond control of many of the drugs till today.

Detailed Answer:
Hi
Welcome for follow up.

* There is possibility of microscopic inflammation even after polyp removal due to
immune disturbances, which is responsible for the report levels.

* No drug can ever keep body system up to date so far as immune response is
concerned, as it is of multiple level controls beyond scope of certain medications still in
today`s era.

* Regular consultation with doctor, periodic colonoscopy are the best tools for her
best future health.

My suggestion would be rather to keep most concern over the symptoms and patient well being over the period of time ; rather than predicting to get Calprotectin level in certain level for always.

Regards.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
doctor
Answered by Dr. Bhagyesh V. Patel 0 minute later
Brief Answer:
immune mechanics beyond control of many of the drugs till today.

Detailed Answer:
Hi
Welcome for follow up.

* There is possibility of microscopic inflammation even after polyp removal due to
immune disturbances, which is responsible for the report levels.

* No drug can ever keep body system up to date so far as immune response is
concerned, as it is of multiple level controls beyond scope of certain medications still in
today`s era.

* Regular consultation with doctor, periodic colonoscopy are the best tools for her
best future health.

My suggestion would be rather to keep most concern over the symptoms and patient well being over the period of time ; rather than predicting to get Calprotectin level in certain level for always.

Regards.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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