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Are Signs And Symptoms Of Fibromyalgia Similar To Lyme Disease?
Question: I am just hoping anyone can clarify if any of this points to lyme OR some other disease Please answer with care and caution as if i was your patient sitting right in front of you.
Sedr rate 50mm
C reactive 0.9mg
Western blot band present 23Da
It said 2 or more bands needed to be present to be positive
That was IgM Ab above
The other lymes test IgG Ab was no bands present
Vitamin b12 flagged high 967 pg/mL
Lyme disease antibodies test 1.19 IV high positive
Red blood count was slightly low at 4.19 M/uL
Total protein high 8.4 g/dL- albumin 4.4 globulin 4.0 gamma 1.70 (ive never been told i have kidney, liver, or hiv problems)
Vitamin d 14 low
Immunoglobulin A abnormal at 299 mg/dL
Thyroid peroxidase antibodies 142.8 IU/mL very very high
They say I have fibromyalgia, and micro papillary thyroid cancer other than that have not been able to figure out why the high sed rate or why the high total proteins in particular i think Gamma was the higher one. I had MRI, CT Scan, Nerve Tests. All found nothing. (i have micro papillary thyroid cancer as a side note)
Sedr rate 50mm
C reactive 0.9mg
Western blot band present 23Da
It said 2 or more bands needed to be present to be positive
That was IgM Ab above
The other lymes test IgG Ab was no bands present
Vitamin b12 flagged high 967 pg/mL
Lyme disease antibodies test 1.19 IV high positive
Red blood count was slightly low at 4.19 M/uL
Total protein high 8.4 g/dL- albumin 4.4 globulin 4.0 gamma 1.70 (ive never been told i have kidney, liver, or hiv problems)
Vitamin d 14 low
Immunoglobulin A abnormal at 299 mg/dL
Thyroid peroxidase antibodies 142.8 IU/mL very very high
They say I have fibromyalgia, and micro papillary thyroid cancer other than that have not been able to figure out why the high sed rate or why the high total proteins in particular i think Gamma was the higher one. I had MRI, CT Scan, Nerve Tests. All found nothing. (i have micro papillary thyroid cancer as a side note)
Brief Answer:
Fibromyalgia vs Lyme disease and papillary thyroid cancer
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
According to current criteria adopted by the CDC, an IgM western
blot is considered positive if two of the following three bands are present:
23, 39, and 41 kDa.You have mentioned that you have only 23 kDa is postive in your case.Hence it is most likely false positive for Lyme disease.Misinterpretation
of IgM blots has been a factor in the incorrect diagnosis of Lyme disease
in patients with other illnesses.
An IgG blot is considered positive if 5 of the following 10 bands are present: 18, 23, 28, 30, 39, 41, 45,58, 66, and 93 kDa.in your case no band was present.
Hence overall you are not serologically positive for Lyme disease and it is ruled out.
The second-generation serologic test is the VlsEC6 peptide IgG ELISA. However this test is not quite as specific as western blot and two-test approach that includes western blot is still recommended.Please upload Lyme disease antibodies test 1.19 IV report for perusal.
ESR(in your case 50 mm fall/hour) is non-specific and can be elevated in many chronic illnesses.
You have in addition low Vit D level ( commonly due to lack of exposure to sun) .
You have also high Vitamin B12 level. Vitamin B12 level can be elevated in various malignancies. You have already been diagnosed as having Papillary carcinoma of thyroid and that can explain high Vitamin B12 level.
You are having slight anemia(Red blood count at 4.19 M/uL).
Since thyroid peroxidase is very high,you might have undergone thyroid function tests like free T3,free T4 & TSH. If you can upload the report,it will be helpful.
Your gamma globulin and so also Immunoglobulin A is also high which usually occurs in chronic liver disease and many other chronic condition.No specific deduction can be made from the input so far.What about your drinking habit.
The most common differential diagnosis of Lyme disease is fibromyalgia . The symptoms may be similar to or indistinguishable from fibromyalgia . Your treating doctor will be the best judge as fibromyalgia is essentially a clinical diagnosis.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Fibromyalgia vs Lyme disease and papillary thyroid cancer
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
According to current criteria adopted by the CDC, an IgM western
blot is considered positive if two of the following three bands are present:
23, 39, and 41 kDa.You have mentioned that you have only 23 kDa is postive in your case.Hence it is most likely false positive for Lyme disease.Misinterpretation
of IgM blots has been a factor in the incorrect diagnosis of Lyme disease
in patients with other illnesses.
An IgG blot is considered positive if 5 of the following 10 bands are present: 18, 23, 28, 30, 39, 41, 45,58, 66, and 93 kDa.in your case no band was present.
Hence overall you are not serologically positive for Lyme disease and it is ruled out.
The second-generation serologic test is the VlsEC6 peptide IgG ELISA. However this test is not quite as specific as western blot and two-test approach that includes western blot is still recommended.Please upload Lyme disease antibodies test 1.19 IV report for perusal.
ESR(in your case 50 mm fall/hour) is non-specific and can be elevated in many chronic illnesses.
You have in addition low Vit D level ( commonly due to lack of exposure to sun) .
You have also high Vitamin B12 level. Vitamin B12 level can be elevated in various malignancies. You have already been diagnosed as having Papillary carcinoma of thyroid and that can explain high Vitamin B12 level.
You are having slight anemia(Red blood count at 4.19 M/uL).
Since thyroid peroxidase is very high,you might have undergone thyroid function tests like free T3,free T4 & TSH. If you can upload the report,it will be helpful.
Your gamma globulin and so also Immunoglobulin A is also high which usually occurs in chronic liver disease and many other chronic condition.No specific deduction can be made from the input so far.What about your drinking habit.
The most common differential diagnosis of Lyme disease is fibromyalgia . The symptoms may be similar to or indistinguishable from fibromyalgia . Your treating doctor will be the best judge as fibromyalgia is essentially a clinical diagnosis.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Above answer was peer-reviewed by :
Dr. Yogesh D
Brief Answer:
Fibromyalgia vs Lyme disease and papillary thyroid cancer
Detailed Answer:
You have been thoroughly investigated as I go through your lab reports.
Microscopic PTC (Papillary Thyroid Cancer) lesions are very small (several millimeters) and are not usually clinically significant and have excellent prognosis except stage IV disease.
Your Immunoglobulin A titre is within reference range.
You have been evaluated also for Celiac disease.
Aches and pains can be due to Rheumatoid arthritis (RA) particularly in female but both RA factor and anti-CCP antibodies are negative and hence excluded.
Your antinuclear antibodies (screening for Systemic lupus erythematosus/SLE to account for aches and pains) are also negative .
Some persons with TPO(thyroid peroxidase) antibodies may not have thyroid dysfunction (your Free thyroxine and TSH are within range). However, the presence of TPO antibodies may increase the risk of future thyroid dysfunction particularly hypothyroidism and will require periodic thyroid function tests monitoring.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Fibromyalgia vs Lyme disease and papillary thyroid cancer
Detailed Answer:
You have been thoroughly investigated as I go through your lab reports.
Microscopic PTC (Papillary Thyroid Cancer) lesions are very small (several millimeters) and are not usually clinically significant and have excellent prognosis except stage IV disease.
Your Immunoglobulin A titre is within reference range.
You have been evaluated also for Celiac disease.
Aches and pains can be due to Rheumatoid arthritis (RA) particularly in female but both RA factor and anti-CCP antibodies are negative and hence excluded.
Your antinuclear antibodies (screening for Systemic lupus erythematosus/SLE to account for aches and pains) are also negative .
Some persons with TPO(thyroid peroxidase) antibodies may not have thyroid dysfunction (your Free thyroxine and TSH are within range). However, the presence of TPO antibodies may increase the risk of future thyroid dysfunction particularly hypothyroidism and will require periodic thyroid function tests monitoring.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Kampana
Answered by
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