Are elevated creatinine levels signs of kidney failure?
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Thanks for the query
I understand you are concerned about your slightly high creatinine. However if i were to be your doctor I wouldn't worry about it as you have no other signs or symptoms of kidney disease for example protein loss in Urine , hypertension, size of the kidney is also normal.
Slightly higher creat is seen in a few conditions, please get back to me with the following
1. are you heavily built and do you exercise daily or lift heavy weights?
2. do you have any family history of kidney disease?
3. do you have history of recurrent urinary tract infections
4. please mention any drugs you might be on, including recreational drugs ( if any)
Please get back to me , I am awaiting your reply
I was also wondering how often do you see elevated creatinine without changes in urinalysis and normal BUN in early stages of renal failure? I thought the BUN and creatinine should be raising simultaneously as the renal function declines. Is that true? Thank you for your help.
Dont see it often
Thanks for getting back. I understand how tensed you might be. Here are the answer to your questions. I will address them one by one so that I dont miss any
1. Occasional ibuprofen should not lead to kidney disease. Even otherwise urine analysis would have shown positive findings if it all anlagesics were to be the cause of kidney injury
2. We do see slightly elevated creat in normal individuals. I have 4 such patients, 1 has no apparent cause, 2 are from the army and 1 is a body builder. Higher creat is often seen in muscular men
3. BUN and creat usually increase simultaneously as renal function declines. That is correct
Now, to solve your apprehension I suggest you to get a DTPA scan done, this will tell us the exact functioning of your kidneys. If this is normal then you have nothing to worry about. Please speak to your doctor regarding this.
I hope I was of help, if you have any further queries please get back to me
Am I still to expect an answer or we are out of time and questions? Either way, thank you for your answers, it really made me feel better about this.
Explanation of eGFR
Thanks for getting back, I am sorry for the short delay in reply. There were two transplants happening in our unit so I got held up.
Now, 'e'gfr means that they have come to the conclusion of gfr by using a formula which has several variables like you have mentioned. It also includes race. It is just an estimate and not a true value.
I still recommend you to undergo Dtpa scan however the gold standard would be to do a renal biopsy but that's an invasive procedure so I wouldn't advice that right away
I am sorry for the short delay once again
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