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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are elevated APTT and fibrinogen levels during pregnancy worrisome?

Answered by
Dr. Rakhi Tayal


Practicing since :2001

Answered : 13424 Questions

Posted on Thu, 6 Dec 2018 in Pregnancy
Question: please review lab results. 34 weeks pregnant , been feeling a tad off. went to the er yesterday and took labs and was sent home before labs came in. I suffer from severe anxiety, are any of these results concerning? can you tell if i have any clotting issues?
Answered by Dr. Rakhi Tayal 1 hour later
Brief Answer:

These are normal. No need to worry.

Detailed Answer:


Thanks for posting your query.

I have seen all the attached reports. The raised levels of APTT and fibrinogen are normal during pregnancy. This does not indicate any clotting issues.

Pregnancy-induced hypercoagulability is probably a physiologically adaptive mechanism to prevent post partum hemorrhage.

Pregnancy changes the plasma levels of many clotting factors, such as fibrinogen, which can rise up to three times its normal value. Thrombin levels also increase during pregnancy.

I hope this answers your query.

Wishing you good health.


Dr. Rakhi Tayal

Above answer was peer-reviewed by : Dr. Nagamani Ng

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