Are anxiety and depression heritable?

default
Posted on Fri, 5 Aug 2016 in Genetics
Question: Today I took a genetic test to try to find out of there might be a genetic predisposition that causes me not to respond to drugs to treat anxiety and depression. What is the liklihood of this? What treatment would work if this is the case?
doctor
Answered by Dr. Diptanshu Das 3 hours later
Brief Answer:
The key lies in developing coping mechanisms

Detailed Answer:
Thanks for asking on HealthcareMagic.

I have gone through your query and understand your concerns. I do not think that genetic testing is going to help. Although anxiety and depression do have genetic predisposition, it is multifactorial and multigenic. It should not be hard for you to detect whether you are prone to anxiety and depression. If you are, you are the best person to deal with it.

Adversaries are there around all of us. We need to understand that things would never go our way. The key is in acceptance of the fact. There are some who embrace the fact and fight back hard. Others, who cannot embrace the fact, go into anxiety and depression.

You are are asking about the likelihood for this. The answer lies with you. Think of it as the likelihood of failure. Failures come but are never final and permanent. The one who does not give up, ultimately wins, no matter how many failures come in the way. If you tend to give up easily, and cannot embrace failure, anxiety and depression is for you. If you are not fond of anxiety and depression, learn to fight back. If you are having problems but have the urge, psychotherapy can help.

I hope that I have been able to clarify.

Feel free to write back in case of further queries.

Regards
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
default
Follow up: Dr. Diptanshu Das 16 minutes later
Very good advice! However, I think I may have been unclear in my question. I have suffered from anxiety and depression most of my life. Thus far I have tried 9 different medications to no avail. My psychiatrist recommended genetic testing to see if perhaps I don't or can't produce serotonin among other possible genetic conditions that might render anti depressants ineffective for me. I was wondering if you knew how common this is and if it is the case for me, what treatments might help.

thanks so much for your help!
doctor
Answered by Dr. Diptanshu Das 1 hour later
Brief Answer:
Genetic testing is not frequently done, hence prevalence data lacking

Detailed Answer:
Thanks for clarifying. Indeed problems of serotonin synthesis, dopamine synthesis or deficiency of serotonin transporter are the most significant cause behind anxiety and depression. Genetic predisposition is not unlikely. I do not have exact statistical data about how common it is but it is not quite uncommon. It might be a good idea to get yourself genetically tested but the issue is that whenever we do some investigation, we do it for the sake of modification of intervention and not merely for the sake of knowing. The issue is that even if you are found to be genetically predisposed, there are no special interventions available.

The following links could be useful for you:
XXXX
XXXX
XXXX

Regards
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
Answered by
Dr.
Dr. Diptanshu Das

Pediatrician

Practicing since :2005

Answered : 3815 Questions

premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions
Drug/Medication
Treatment/Therapy
Lab Tests

Recent questions on  Dopamine

doctor1 MD

Hello Sir

I have been over-masturbating and I'm experiencing these symptoms :

-Sadness
-Memory loss
-Lack of concentration
-Fatigue. Feeling tired...

doctor1 MD

Sub: Drug Treatment for Parkinson s Disease What is of the counter Chemist name for purchase of the drug ? Drug Sinemet (Levodopa/Carbidopa)....

doctor1 MD

Can discontinuation of perscription adderall cause muscle aching? What does adderall do to muscle tissue? Thank you.

doctor1 MD

TruWeight & Energy Active Ingredients List: (Listed Alphabetically) AMP: AMP is found in Phuong Tea and acts as a metabolism “booster” and assists...

doctor1 MD

I have been on Cymbalta for 3 years approximately. So we tried Prozak 40mg BID. It doesn't seem to make any difference. I did ween myself off of...

doctor1 MD

Why is the medical disorder of epilepsy frequently misdiagnosed as a psuedoseizure requiring the care of a psychiatrist, as well as psychotropic...

Get personalised answers from verified doctor in minutes across 80+ specialties

122 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
backtotop2