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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are Diminutive polyps genetic due to a family history of colon cancers?

Answered by
Dr. T Chandrakant

General Surgeon

Practicing since :1984

Answered : 12170 Questions

Posted on Fri, 4 Jan 2019 in Abdominal Pain
Question: my Age is 35 / male

Taking pan d for the past 4 months
For reflux related issues
Last week had gastritis symptoms which was not responding to PPI
So doctor adviced for endoscopy

Diminutive polyp
H pylori negative

Family history
Grandfather died due to colon cancer age 75

My question
Can this polyp is related to genetic
Really scared after checking it on internet like FAP
Tissue sample sent for biopsy
But any idea what this can be
Answered by Dr. T Chandrakant 1 hour later
Brief Answer:

As detailed below.

Detailed Answer:


Grossly the diminutive polyp cannot be reliably distinguished from a hyperplastic pseudopolyp vs. a small true polyp (adenoma), and hence all such lesions are removed for microscopic analysis.

So the diminutive polyp in your case may be a hyperplastic small lesion.

If the lesion is single then this may not be related to genetics.
FAP have a typical appearance, hence should have been mentioned if present by your Endoscopist.

So stop worrying till the biopsy report is available.
Avoid the stress and anxiety as these can be one of the reasons for gastritis and reflux not responding to PPI.

Hope I have answered your query. Let me know if I can assist you further.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
Follow up: Dr. T Chandrakant 16 hours later
Thankyou for your reply
I have sent pictures of my endoscopic result
Please send me ur comments
Answered by Dr. T Chandrakant 2 hours later
Brief Answer:

Please post reports of biopsy

Detailed Answer:


Polyps look small without much signs of any dangerous problems.
Well, it is always the histopathology report that clears the doubts. Awaiting the reports.

Hope I have answered your query.

Take care

Dr T Chandrakant, General Surgeon
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

The User accepted the expert's answer

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