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What does high MVP level indicate? - Online Doctor Chats

Date : 25-Mar-2014
User rating for this question
Very Good Posted in: X-ray, Lab tests and Scans
Answered by

General & Family Physician
Practicing since : 2005
Answered : 2568 Questions
User:I have recently had blood work done. My chloride came back high at 108, platelet count came back low at 149, MPV came back high at 10.3 and AST(SGOT) at a low 10. I have had blood work done 4 times in the past year and my platelets always tend to run on the low end, twice being below the low end by a few points. The doctor that I am seeing did not say anything to me about these abnormal readings. I found out when I requested my paperwork for my personal files. Can you advise on why these numbers could be off and if I should be overly worried? Thank you!
Doctor:please give me a moment to go through your query
User:Thank you
Doctor:AST and Chloride levels don't mean much
Doctor:I wouldn't give them too much importance
Doctor:MPV is on the higher side, and that according to some recent science means you have a higher risk for cardiovascular accidents
User:I would also like to add that my vision in the right eye was a bit blurry on and off for these two weeks. I did see the opthomologist and nothing was wrong there. I also have been to the neurologist twice over it.
Doctor:Are you diabetic or hypertensive?
User:No, I am not diabetic and even used a blood sugar monitor for a few days to make sure I wasn't having problems with that. All other blood work has come back great. Cholesterol is great and blood pressure has always been low in the high 90s over 60s.
Doctor:We currently do not understand completely why the platelet volume increases.
Doctor:Okay, that is quite reassuring
Doctor:if you are not a diabetic or hypertensive, and you have cholesterol that is fantastic
Doctor:You can safely neglect this MPV for the time being
User:Platelet volume meaning MPV?
Doctor:Yes, MPV is mean platelet volume
Doctor:as for the low platelet counts, it is not alarmingly low, it is just 1 thousand under the normal cut off of 150000 per cubic mm
Doctor:That can happen if you had had a recent viral infection of any sort
User:As for the low platelet level, is there anything that I should be concerned about or can you give me advise on what I should be tested for? I have recently had C-Reactive Protein tests, Ana screen, IFA, SED Rate by modified Westergren, and that all came back good with no concern.
Doctor:and if you had an infection, that would explain the slightly raised MPV as well
Doctor:Your tests returning good is again very good
Doctor:I would only like to add another test, that is "Antiplatelet antibody levels"
Doctor:get this test done to see if your platelets are being destroyed by some antibodies against them
User:If I had an infection, I am don't know about it. What would cause platelets to be destroyed?
Doctor:other than that, the gold standard for blood cell related issues is to go for a bone marrow study
Doctor:In infections, not only do platelets and white blood cells get destroyed to some extent, their production can go down a little bit as well
User:Did you see the part about my facial numbness and prickly feeling for two weeks? Could this possibly be caused by any of this or bone marrow problems?
Doctor:Yes, I read that as well
Doctor:and I do not think these two are related in any way
Doctor:Bone marrow problems do not cause those symptoms at all
User:That is good to know. Do you have any ideas about the facial problems? All the doctors I have seen don't seem to know why it was caused. They thought maybe shingles was starting, which I have had when I was 21.
Doctor:Facial numbness could be because of a viral infection (happens some times when the facial nerve gets a bit inflamed due to the infection)
Doctor:Yes, Shingles can cause such sensations
User:Have you ever heard of shingles symptoms like that but never develop into an actual rash?
Doctor:other causes are parotid inflammation
Doctor:yes, I have seen such cases indeed
Doctor:is there anything else I can help you with?
User:One more question. I have been low on Vitamin D for over a year now. I do take supplements for this. My hair began falling out more than usual a little over a year ago. I have been through all kinds of hormone tests and blood work. They all come back fine. Besides me just getting older, do you have any ideas about that?
Doctor:36 years is not old
User:I said older, not old. ;-)
Doctor:hair loss could be due to stress
Doctor:Oh.. okay, sorry for that
User:You don't see any correlation between any of that and the Vitamin D deficiency and the other problems I have been having, low platelets etc.?
Doctor:other than that, if your hormone levels are fine, then I can't think of anything significant
User:Thank you so much for your time and input. I hope you have a great weekend.
Doctor:Vitamin D deficiency does not cause platelet abnormalities
Doctor:and it does not cause the facial numbness either
User:Good to know that too.
Doctor:Okay, thank you for using the service
Doctor:It was my pleasure to answer your queries
Doctor:I hope you will have a great weekend too
Doctor:Have a good evening, and take care
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