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What causes raised D dimer? - Online Doctor Chats

Date : 19-Apr-2014
User rating for this question
Very Good Posted in: Lung and Chest disorders
Answered by

General & Family Physician
Practicing since : 2005
Answered : 2585 Questions
User:Three years ago I had a high d-dimer result, lung CT was done, it was negative. Christmas day 2013 went to ER because of dizziness. D-dimer was high again, another lung CT negative. A week ago I went to urgent care because of some pain in my chest. Cardiac panel showed high d-dimer again!!!! Doctor freaks out, sends to the ER, the ER doc sends me home because he said it was the same as it was in Dec., and no blood clot then. Went to urgent care again, still worried about pain in chest (I am now realizing it was probably pulled muscles.) That dr. is freaking out about the high d-dimer. I told him what I just told you. He ordered an RA test. It was negative. So, I will tell you I have had chronic back pain for 15 years. Is inflammation from this kind of pain enough to cause a high d-dimer? I take Arthrotec and wellbutrin for medications. Could medications cause a high result? I plan to call the latest urgent care dr. and the ER doc and see what they think it is before my visit to my regular doctor. How common is a high d-dimer result when there is nothing wrong? Is my chronic pain the cause of the high d-dimer? I am just looking for a few different opinions. Thank you.
Doctor:Give me a moment to read your query
Doctor:I have read your query
Doctor:D dimer is raised in many conditions
Doctor:One is deep vein thrombosis and pulmonary embolism
Doctor:But there are many benign condition that can cause a high d dimer
Doctor:These conditions include surgery, trauma, infection, pregnancy, liver issues, etc
Doctor:Sometimes it may be falsely positive
Doctor:Chronic pain can also cause high d-dimer levels
Doctor:Do you have any doubts here?
User:I do not have any of the above condition that you mentioned, except the chronic pain. I have been reading that cancers can cause a high d-dimer or heart disease. I just don't what if any, other tests should be done on me.
Doctor:Looking at your age, you can go for some screening tests for some common cancers
Doctor:Otherwise you do not need to be checked for cancers just because d-dimers are high
Doctor:The cancers that need to be ruled out for your age are breast cancer, cervical cancer. fobt for colon cancer
User:I had a colonoscopy last August, it was normal. I had a mammogram in Sept., also normal. Going for a breast MRI because my sister had breast cancer so dr. suggested that every 6 months, mammogram and MRI. Paps have been negative
Doctor:So you are mostly in great health
Doctor:except for some back pain and raised d-dimer
Doctor:Do you have any doubts here?
User:The chronic pain keeps me from getting enough exercise. Yes, darn d-dimer, just wish I knew what it meant, if it means anything. The urgent care dr. is one I really like and he was concerned. He really thought the RA test would be positive but it wasn't.
Doctor:Have you gotten liver function tests recently like sgot, sgpt, serum bilirubin
User:No I don't think so
Doctor:It alone does not mean anything unless you have some other issues with it
Doctor:Since d-dimer is excreted by liver it can be done
Doctor:It is part of routine blood tests
Doctor:Otherwise I dont think there is much to worry
User:O.K. So some people just have a high d-dimer and it doesn't mean anything?
User:O.K., thank you, this helps! Have a great day!
Doctor:Thanks for coming on chat
Doctor:You too have a great time
User:Thank you
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