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Overr dose of perntobarbitol - Online Doctor Chats

Date : 13-Jan-2012
User rating for this question
Very Good Posted in: General Health
Answered by

General & Family Physician
Practicing since : 2008
Answered : 3622 Questions
User :   Anestesal is a veterinarian euthanasia drug containing the barbiturate pentobarbital. If a person ingested 12 grams of pentobarbital, what would happen? I am interested because I am conducting a study on physician-assisted euthanasia.

Also, does age play a factor? What if a person is perfectly healthy and has no terminal illness? Will this still be fatal?
User :   hello?
Doctor :   hi
User :   Can you see my question above?
Doctor :  
please give me time to read and reply
User :   oh ok, sry
Doctor :  
no no dont be sorry
Doctor :  
phenobarbitone is used as a drug for the treatment of some diseases like convulsions(fits)
Doctor :   anxiety,insomnia
User :   and pentobarbital?
User :   brand names are also Nembutal, Anestesal
Doctor :  
Barbiturates mainly act in the CNS, though they may indirectly affect other organ systems. Direct effects include sedation and hypnosis at lower dosages
User :   What is the lethal dosage of pentobarbital?
User :   The state of oregon uses 10 grams of orally ingested pentobarbital in physician assisted deaths
User :   But no one is able to give a definite amount
Doctor :   3 times that of normal dose
User :   what is the normal dose?
Doctor :  
is poisonous
User :   What are the chances of surviving 12 grams of orally ingested pentobarbital?
Doctor :  
normal is 1 gram per 10 grams is lethal;
Doctor :  
to be precise
Doctor :  
sorry 1gram for 1okg of body weight
User :   what is okg?
User :   oh
User :   10 kilograms
Doctor :  
Doctor :  
10 kg
User :   so 70 kilograms means the 7 grams of pentobarbital, i understand
Doctor :   give me 2 minutes please

Doctor :   yes
User :   so a patient who is 70kg ingests at least 7 grams of pentobarbital
User :   what happens immediately after ingestion?
Doctor :  
Phenobarbital causes a "depression" of the body's systems, mainly the central and peripheral nervous systems;
User :   but what about pentobarbital?
Doctor :   sorry
Doctor :   i typed pheno instead of pento
User :   immediate unconsciousness, coma, death?
User :   Doctor, I have to go
User :   I have an appointment
Doctor :   main characteristic of ppbarbital overdose is a "slowing" of bodily functions, including decreased consciousness (even coma), bradycardia, bradypnea, hypothermia, and hypotension (in massive overdoses).
Doctor :  
Doctor :  
Doctor :  
take care
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