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Mycobacterium tuberculosis and its detection - Online Doctor Chats

Date : 13-Jan-2012
User rating for this question
Very Good Posted in: Lung and Chest disorders
Answered by

General & Family Physician
Practicing since : 2008
Answered : 3631 Questions

Doctor :   Hi
Doctor :  
how can i help you?
User :   Could you help me with a few queries on latent Tuberculosis?

1) Is the diagnosis of Latent TB (LTB) possible only via history,cxr, mantoux and IGRA?
2) Where do the M.tuberculosis bacilli get confined in their dormant state?
3)What is the status of AFB in LTB?.. can LTB patients be AFB positive?
4)Can M.tuberculosis be isolated from any of the body fluids or biopsied from anywhere in case of LTB ?
Doctor :   i shall take a min to read
User :   ok
Doctor :  
latent TB can be diagnosed if there is signs in CXR
User :   but that goes against ltb
User :   ltb usually does not have cxr signs
Doctor :   PCR analysis can be useful in cases of no chest signs and CXR is normal
User :   pcr is not a gold standard
User :   i specifically am looking for information on afb status in ltb
User :   can afb be demonstrated in ltb patients
Doctor :  
Latent tuberculosis is where a patient is infected with Mycobacterium tuberculosis, but does not have active tuberculosis disease.

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